Hierarchically porous bioactive glass scaffolds synthesized with a PUF and P123 cotemplated approach

Xia Li, Xiupeng Wang, Hangrong Chen, Peng Jiang, Xiaoping Dong, Jianlin Shi

Research output: Contribution to journalArticlepeer-review

122 Scopus citations

Abstract

Hierarchically porous bioactive glass (CaO-SiO2-P 2O5) scaffolds have been prepared by using nonionic block copolymer EO20PO70EO20 (P123) and polyurethane (PUF) as cotemplates. It exhibits a hierarchical structure with interconnected macropores (about 200-400 or 500-700 μm), which provide the potential for tissue ingrowth and the neovascularization, and uniform mesopores (3.68 nm), which cause an increase in the specific surface area and enhanced bioactivity and release of ionic products. The ordered hierarchically porous scaffold has the advantages of both mesoporosity and macroporosity, which may find potential applications in tissue engineering and drug storage.

Original languageEnglish
Pages (from-to)4322-4326
Number of pages5
JournalChemistry of Materials
Volume19
Issue number17
DOIs
StatePublished - 21 Aug 2007
Externally publishedYes

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