Gold nanoparticle-based sensing strategies for biomolecular detection

Lihua Wang; Shiping Song; Dun Pan; Di Li; Chunhai Fan

doi:10.1351/PAC-CON-09-01-20

Gold nanoparticle-based sensing strategies for biomolecular detection

Lihua Wang, Shiping Song, Dun Pan, Di Li, Chunhai Fan^*

^*Corresponding author for this work

Chinese Academy of Sciences

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Gold nanoparticles (AuNPs) have been extensively employed in biological studies for several decades. More recently, progress has well demonstrated that DNA-conjugated AuNPs are highly promising nanoprobes for the sensitive detection of various biomolecules, based on the unique optical and electronic properties of AuNPs. In this short review, we focus on the use of AuNP-based nanoprobes for biological detection of nucleic acids, proteins, and other biologically relevant small-molecule targets, mainly based on the recent progress in our laboratory.

Original language	English
Pages (from-to)	81-89
Number of pages	9
Journal	Pure and Applied Chemistry
Volume	82
Issue number	1
DOIs	https://doi.org/10.1351/PAC-CON-09-01-20
State	Published - 2010
Externally published	Yes

Keywords

Biosensors
DNA
Gold nanoparticles
Nanoprobes
Surface plasmon resonance

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10.1351/PAC-CON-09-01-20

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abstract = "Gold nanoparticles (AuNPs) have been extensively employed in biological studies for several decades. More recently, progress has well demonstrated that DNA-conjugated AuNPs are highly promising nanoprobes for the sensitive detection of various biomolecules, based on the unique optical and electronic properties of AuNPs. In this short review, we focus on the use of AuNP-based nanoprobes for biological detection of nucleic acids, proteins, and other biologically relevant small-molecule targets, mainly based on the recent progress in our laboratory.",

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AU - Song, Shiping

AU - Pan, Dun

AU - Li, Di

AU - Fan, Chunhai

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AB - Gold nanoparticles (AuNPs) have been extensively employed in biological studies for several decades. More recently, progress has well demonstrated that DNA-conjugated AuNPs are highly promising nanoprobes for the sensitive detection of various biomolecules, based on the unique optical and electronic properties of AuNPs. In this short review, we focus on the use of AuNP-based nanoprobes for biological detection of nucleic acids, proteins, and other biologically relevant small-molecule targets, mainly based on the recent progress in our laboratory.

KW - Biosensors

KW - DNA

KW - Gold nanoparticles

KW - Nanoprobes

KW - Surface plasmon resonance

UR - https://www.scopus.com/pages/publications/76049087600

U2 - 10.1351/PAC-CON-09-01-20

DO - 10.1351/PAC-CON-09-01-20

M3 - 文章

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JO - Pure and Applied Chemistry

JF - Pure and Applied Chemistry

IS - 1

ER -

Gold nanoparticle-based sensing strategies for biomolecular detection

Abstract

Keywords

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