Abstract
The direct conversion of C-H bond into C-X bond has been emergent as an efficient approach for the construction of complex molecules. In this area, gold-catalyzed C(sp[[sup]]2[[/sup]])-H bond functionalization has attracted great interest over the past two decades as a synthetic toolbox for the construction of complex molecules and late-stage modification of bioactive compounds. This article summarizes the evolution of gold-catalyzed C(sp[[sup]]2[[/sup]])-H bond functionalization and exhibits the different chemo- and site-selectivities under various reaction conditions.
| Original language | English |
|---|---|
| Title of host publication | Handbook of CH-Functionalization |
| Publisher | wiley |
| Pages | 1-42 |
| Number of pages | 42 |
| ISBN (Electronic) | 9783527834242 |
| DOIs | |
| State | Published - 1 Jan 2022 |
Keywords
- C-H bond functionalization
- carbon-carbon bond
- carbon-heteroatom bond
- Gold catalysis
- selectivity