Glucose biosensor based on Au nanoparticles-conductive polyaniline nanocomposite

Yuezhong Xian; Yi Hu; Fang Liu; Yang Xian; Haiting Wang; Litong Jin

doi:10.1016/j.bios.2005.09.014

Glucose biosensor based on Au nanoparticles-conductive polyaniline nanocomposite

Yuezhong Xian
, Yi Hu
, Fang Liu
, Yang Xian
, Haiting Wang
, Litong Jin^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

263 Scopus citations

Abstract

In this paper, we report a novel glucose biosensor based on composite of Au nanoparticles (NPs)-conductive polyaniline (PANI) nanofibers. Immobilized with glucose oxidase (GOx) and Nafion on the surface of nanocomposite, a sensitive and selective biosensor for glucose was successfully developed by electrochemical oxidation of H₂O₂. The glucose biosensor shows a linear calibration curve over the range from 1.0 × 10^-6 to 8.0 × 10^-4 mol/L, with a slope and detection limit (S/N = 3) of 2.3 mA/M and 5.0 × 10^-7 M, respectively. In addition, the glucose biosensor system indicates excellent reproducibility (less than 5% R.S.D.) and good operational stability (over 2 weeks).

Original language	English
Pages (from-to)	1996-2000
Number of pages	5
Journal	Biosensors and Bioelectronics
Volume	21
Issue number	10
DOIs	https://doi.org/10.1016/j.bios.2005.09.014
State	Published - 15 Apr 2006

Keywords

Au nanoparticles
Glucose biosensor
Polyaniline nanofibers

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10.1016/j.bios.2005.09.014

Cite this

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title = "Glucose biosensor based on Au nanoparticles-conductive polyaniline nanocomposite",

abstract = "In this paper, we report a novel glucose biosensor based on composite of Au nanoparticles (NPs)-conductive polyaniline (PANI) nanofibers. Immobilized with glucose oxidase (GOx) and Nafion on the surface of nanocomposite, a sensitive and selective biosensor for glucose was successfully developed by electrochemical oxidation of H2O2. The glucose biosensor shows a linear calibration curve over the range from 1.0 × 10-6 to 8.0 × 10-4 mol/L, with a slope and detection limit (S/N = 3) of 2.3 mA/M and 5.0 × 10-7 M, respectively. In addition, the glucose biosensor system indicates excellent reproducibility (less than 5\% R.S.D.) and good operational stability (over 2 weeks).",

keywords = "Au nanoparticles, Glucose biosensor, Polyaniline nanofibers",

author = "Yuezhong Xian and Yi Hu and Fang Liu and Yang Xian and Haiting Wang and Litong Jin",

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doi = "10.1016/j.bios.2005.09.014",

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TY - JOUR

T1 - Glucose biosensor based on Au nanoparticles-conductive polyaniline nanocomposite

AU - Xian, Yuezhong

AU - Hu, Yi

AU - Liu, Fang

AU - Xian, Yang

AU - Wang, Haiting

AU - Jin, Litong

PY - 2006/4/15

Y1 - 2006/4/15

N2 - In this paper, we report a novel glucose biosensor based on composite of Au nanoparticles (NPs)-conductive polyaniline (PANI) nanofibers. Immobilized with glucose oxidase (GOx) and Nafion on the surface of nanocomposite, a sensitive and selective biosensor for glucose was successfully developed by electrochemical oxidation of H2O2. The glucose biosensor shows a linear calibration curve over the range from 1.0 × 10-6 to 8.0 × 10-4 mol/L, with a slope and detection limit (S/N = 3) of 2.3 mA/M and 5.0 × 10-7 M, respectively. In addition, the glucose biosensor system indicates excellent reproducibility (less than 5% R.S.D.) and good operational stability (over 2 weeks).

AB - In this paper, we report a novel glucose biosensor based on composite of Au nanoparticles (NPs)-conductive polyaniline (PANI) nanofibers. Immobilized with glucose oxidase (GOx) and Nafion on the surface of nanocomposite, a sensitive and selective biosensor for glucose was successfully developed by electrochemical oxidation of H2O2. The glucose biosensor shows a linear calibration curve over the range from 1.0 × 10-6 to 8.0 × 10-4 mol/L, with a slope and detection limit (S/N = 3) of 2.3 mA/M and 5.0 × 10-7 M, respectively. In addition, the glucose biosensor system indicates excellent reproducibility (less than 5% R.S.D.) and good operational stability (over 2 weeks).

KW - Au nanoparticles

KW - Glucose biosensor

KW - Polyaniline nanofibers

UR - https://www.scopus.com/pages/publications/33645213159

U2 - 10.1016/j.bios.2005.09.014

DO - 10.1016/j.bios.2005.09.014

M3 - 文章

C2 - 16275055

AN - SCOPUS:33645213159

SN - 0956-5663

VL - 21

SP - 1996

EP - 2000

JO - Biosensors and Bioelectronics

JF - Biosensors and Bioelectronics

IS - 10

ER -

Glucose biosensor based on Au nanoparticles-conductive polyaniline nanocomposite

Abstract

Keywords

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