Generation of MnO                         2                          nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

Qingsong Yang; Li Li; Fang Zhao; Yunwei Wang; Zhishuang Ye; Xuhong Guo

doi:10.1016/j.matlet.2019.04.007

Generation of MnO ₂ nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

Qingsong Yang, Li Li, Fang Zhao, Yunwei Wang, Zhishuang Ye, Xuhong Guo

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Novel MnO ₂ nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO ₂ nanozymes were immobilized in SPB (SPB-MnO ₂ ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO ₂ nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO ₂ /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.

Original language	English
Pages (from-to)	89-92
Number of pages	4
Journal	Materials Letters
Volume	248
DOIs	https://doi.org/10.1016/j.matlet.2019.04.007
State	Published - 1 Aug 2019
Externally published	Yes

Keywords

MnO nanosheets
Nanocomposites
Nanozyme
Polymers
SAXS
Spherical polyelectrolyte brush

Access to Document

10.1016/j.matlet.2019.04.007

Cite this

@article{0c5e7e5a4f5249b896194c5e8b9c9dbe,

title = " Generation of MnO 2 nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione ",

abstract = " Novel MnO 2 nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO 2 nanozymes were immobilized in SPB (SPB-MnO 2 ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO 2 nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO 2 /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.",

keywords = "MnO nanosheets, Nanocomposites, Nanozyme, Polymers, SAXS, Spherical polyelectrolyte brush",

author = "Qingsong Yang and Li Li and Fang Zhao and Yunwei Wang and Zhishuang Ye and Xuhong Guo",

note = "Publisher Copyright: {\textcopyright} 2019",

year = "2019",

month = aug,

day = "1",

doi = "10.1016/j.matlet.2019.04.007",

language = "英语",

volume = "248",

pages = "89--92",

journal = "Materials Letters",

issn = "0167-577X",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Generation of MnO 2 nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

AU - Yang, Qingsong

AU - Li, Li

AU - Zhao, Fang

AU - Wang, Yunwei

AU - Ye, Zhishuang

AU - Guo, Xuhong

PY - 2019/8/1

Y1 - 2019/8/1

N2 - Novel MnO 2 nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO 2 nanozymes were immobilized in SPB (SPB-MnO 2 ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO 2 nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO 2 /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.

AB - Novel MnO 2 nanozymes were prepared as nanosheets in situ using spherical poly[(2-methacryloyloxyethyl) trimethyl ammonium chloride] (PDMC) brushes (SPB) as nanoreactors. The prepared MnO 2 nanozymes were immobilized in SPB (SPB-MnO 2 ) showing high stability and excellent oxidase-like property which could oxidize 3,3′,5,5′-tetramethylbenzidine (TMB) into oxidized TMB (oxTMB), accompanied by the change of absorption at 653 nm. The MnO 2 nanosheets could be decomposed by trace amount of glutathione (GSH) under acidic environment as validated by small angle X-ray scattering (SAXS). The SPB-MnO 2 /TMB system, with a detection limit of 450 nM, should be an ideal candidate for colorimetric detection of GSH. This work opens a new way to prepare highly stable nanozymes for the detection of GSH.

KW - MnO nanosheets

KW - Nanocomposites

KW - Nanozyme

KW - Polymers

KW - SAXS

KW - Spherical polyelectrolyte brush

UR - https://www.scopus.com/pages/publications/85063795161

U2 - 10.1016/j.matlet.2019.04.007

DO - 10.1016/j.matlet.2019.04.007

M3 - 文章

AN - SCOPUS:85063795161

SN - 0167-577X

VL - 248

SP - 89

EP - 92

JO - Materials Letters

JF - Materials Letters

ER -

Generation of MnO ₂ nanozyme in spherical polyelectrolyte brush for colorimetric detection of glutathione

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this