TY - JOUR
T1 - Freestanding germanene nanosheets for rapid degradation and photothermal conversion
AU - Ge, M.
AU - Zong, M.
AU - Xu, D.
AU - Chen, Z.
AU - Yang, J.
AU - Yao, H.
AU - Wei, C.
AU - Chen, Y.
AU - Lin, H.
AU - Shi, J.
N1 - Publisher Copyright:
© 2021 The Author(s)
PY - 2021/8
Y1 - 2021/8
N2 - Germanium plays an important role in biomedical utilizations, mainly for inducing erythropoietic, antimicrobial, antiviral, antimutagenic, and immunomodulating effects. The biological applications of organic germanium have been gradually reported in recent years; however, the intrinsic poor biodegradation of most inorganic nanomaterials prevent their further in vivo applications and clinical translation in biomedicine. Herein, two-dimensional (2D) quasi-freestanding and fully biodegradable germanene nanosheets have been synthesized from Zintl-phase ladder-shaped binary germanide (CaGe2), which feature intriguing physiochemical properties for photo-triggered therapeutics and photoacoustic diagnostic imaging, as well as excellent biocompatibility, in addition to the excellent degradability compared with other typical 2D biomaterials. This work presents a novel type of 2D structured inorganic germanium biomaterial featuring attractive biomedical multifunctionalities, which is expected to benefit clinical and translational medicine.
AB - Germanium plays an important role in biomedical utilizations, mainly for inducing erythropoietic, antimicrobial, antiviral, antimutagenic, and immunomodulating effects. The biological applications of organic germanium have been gradually reported in recent years; however, the intrinsic poor biodegradation of most inorganic nanomaterials prevent their further in vivo applications and clinical translation in biomedicine. Herein, two-dimensional (2D) quasi-freestanding and fully biodegradable germanene nanosheets have been synthesized from Zintl-phase ladder-shaped binary germanide (CaGe2), which feature intriguing physiochemical properties for photo-triggered therapeutics and photoacoustic diagnostic imaging, as well as excellent biocompatibility, in addition to the excellent degradability compared with other typical 2D biomaterials. This work presents a novel type of 2D structured inorganic germanium biomaterial featuring attractive biomedical multifunctionalities, which is expected to benefit clinical and translational medicine.
KW - Germanene
KW - Nanomedicine
KW - Photothermal conversion
KW - Rapid biodegradation
KW - Two-dimensional nanosheets
UR - https://www.scopus.com/pages/publications/85105516246
U2 - 10.1016/j.mtnano.2021.100119
DO - 10.1016/j.mtnano.2021.100119
M3 - 文章
AN - SCOPUS:85105516246
SN - 2588-8420
VL - 15
JO - Materials Today Nano
JF - Materials Today Nano
M1 - 100119
ER -