Fluorescence signal amplification by cation exchange in ionic nanocrystals

Jishan Li*, Tierui Zhang, Jianping Ge, Yadong Yin, Wenwan Zhong

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

61 Scopus citations

Abstract

(Figure Presented) Lighting-up time: A cation-exchange reaction releases thousands of divalent cations from nonfluorescent CdSe ionic crystals and triggers fluorescence of originally nonfluorescent Fluo-4 fluorophores to obtain a large fluorescence amplification (see picture) and a low detection limit in bioassays. simple, with a large dye-to-reporter labeling ratio, and flexible in selection of nanocrystals and fluorophores.

Original languageEnglish
Pages (from-to)1588-1591
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number9
DOIs
StatePublished - 16 Feb 2009
Externally publishedYes

Keywords

  • Fluorescence
  • Ion exchange
  • Ionic nanocrystals
  • Sensors
  • Signal amplification

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