TY - JOUR
T1 - Ferrocene Derivatives Modified MOFs-Based Sensors for Electrochemical Detection of Chloramphenicol
AU - Li, Xu Shan
AU - Du, Jia Qi
AU - Liu, Ming Cheng
AU - Sun, Qian
AU - Gao, En Qing
N1 - Publisher Copyright:
© 2024 The Electrochemical Society (“ECS”). Published on behalf of ECS by IOP Publishing Limited. All rights, including for text and data mining, AI training, and similar technologies, are reserved.
PY - 2024/9/2
Y1 - 2024/9/2
N2 - Although chloramphenicol(CAP) plays a critical role in many medical treatments, its abuse is not only seriously toxic to humans but also ecologically harmful when discharged into the water. Therefore, it is of great significance to realize the rapid and efficient detection of CAP. 2D MOFs Cu3(HITP)2 (HITP = 2,3,6,7,10,11-hexaiminotriphenylene) with higher electrical conductivity than conventional MOFs were synthesized using hydrothermal methods. Fc-NH2, as an electron donor, was dispersed on the surface of MOFs by physical doping. The synthesized nanocomposite Cu3(HITP)2/Fc-NH2 has excellent adsorption properties and electrical conductivity. It was used to construct an electrochemical sensor and exhibited superior performance in the detection of CAP. Electrochemical reduction of CAP on Cu3(HITP)2/Fc-NH2/GCE was investigated using cyclic voltammetry and differential pulse voltammetry. The results show that Cu3(HITP)2/Fc-NH2/GCE has a much wider linear range of 0.5 ∼ 2100 μm than previous studies when detecting CAP. The detection limit is as low as 0.43 μm. The electrochemical sensing platform reported in this work also exhibits excellent reproducibility, selectivity, and stability, and the recovery rate of CAP detection in the actual sample ranged from 97.1% to 102.4%. This work provides a new strategy for antibiotic detection and extends the application of triphenylene-based MOFs in the electrochemical sensing field.
AB - Although chloramphenicol(CAP) plays a critical role in many medical treatments, its abuse is not only seriously toxic to humans but also ecologically harmful when discharged into the water. Therefore, it is of great significance to realize the rapid and efficient detection of CAP. 2D MOFs Cu3(HITP)2 (HITP = 2,3,6,7,10,11-hexaiminotriphenylene) with higher electrical conductivity than conventional MOFs were synthesized using hydrothermal methods. Fc-NH2, as an electron donor, was dispersed on the surface of MOFs by physical doping. The synthesized nanocomposite Cu3(HITP)2/Fc-NH2 has excellent adsorption properties and electrical conductivity. It was used to construct an electrochemical sensor and exhibited superior performance in the detection of CAP. Electrochemical reduction of CAP on Cu3(HITP)2/Fc-NH2/GCE was investigated using cyclic voltammetry and differential pulse voltammetry. The results show that Cu3(HITP)2/Fc-NH2/GCE has a much wider linear range of 0.5 ∼ 2100 μm than previous studies when detecting CAP. The detection limit is as low as 0.43 μm. The electrochemical sensing platform reported in this work also exhibits excellent reproducibility, selectivity, and stability, and the recovery rate of CAP detection in the actual sample ranged from 97.1% to 102.4%. This work provides a new strategy for antibiotic detection and extends the application of triphenylene-based MOFs in the electrochemical sensing field.
KW - composites
KW - electroanalytical electrochemistry
KW - metal-organic frameworks
KW - sensors
UR - https://www.scopus.com/pages/publications/85205148655
U2 - 10.1149/1945-7111/ad7985
DO - 10.1149/1945-7111/ad7985
M3 - 文章
AN - SCOPUS:85205148655
SN - 0013-4651
VL - 171
JO - Journal of the Electrochemical Society
JF - Journal of the Electrochemical Society
IS - 9
M1 - 097513
ER -
