Fe NPs and MWCNTs based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids

Jing Wang; Xueying Liu; Yiting Wang; Lei Yu; Hui Peng; Jian Zhong Zhu

doi:10.1016/j.snb.2016.07.115

Fe NPs and MWCNTs based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids

Jing Wang
, Xueying Liu
, Yiting Wang^*
, Lei Yu
, Hui Peng
, Jian Zhong Zhu

^*Corresponding author for this work

School of Physics and Electronic Science

East China Normal University

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

An amperometric electrode based on multiwall carbon nanotubes (MWCNTs) and Fe nanoparticles (NPs) has been successfully fabricated. The electrode combined with Flow Injection Analysis (FIA) exhibits linear response in the concentration range of 0.1–12 μM and the sensitivity of 30.0 nA μM⁻¹ for most of amino acids, confirming good complexation of amino acids (AAs) with Fe NPs on the modified electrode. The determination of 17 amino acids in the hypothalamus microdialysis fluids of guinea pigs, illustrates that it is a powerful tool to investigate physiology and pathology mechanisms.

Original language	English
Pages (from-to)	834-841
Number of pages	8
Journal	Sensors and Actuators B: Chemical
Volume	238
DOIs	https://doi.org/10.1016/j.snb.2016.07.115
State	Published - 1 Jan 2017

Keywords

Amino acids
Amperometric electrode detector
Fe nanoparticles
Hypothalamus dialysis fluid
Multiwall carbon nanotubes

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10.1016/j.snb.2016.07.115

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title = "Fe NPs and MWCNTs based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids",

abstract = "An amperometric electrode based on multiwall carbon nanotubes (MWCNTs) and Fe nanoparticles (NPs) has been successfully fabricated. The electrode combined with Flow Injection Analysis (FIA) exhibits linear response in the concentration range of 0.1–12 μM and the sensitivity of 30.0 nA μM−1 for most of amino acids, confirming good complexation of amino acids (AAs) with Fe NPs on the modified electrode. The determination of 17 amino acids in the hypothalamus microdialysis fluids of guinea pigs, illustrates that it is a powerful tool to investigate physiology and pathology mechanisms.",

keywords = "Amino acids, Amperometric electrode detector, Fe nanoparticles, Hypothalamus dialysis fluid, Multiwall carbon nanotubes",

author = "Jing Wang and Xueying Liu and Yiting Wang and Lei Yu and Hui Peng and Zhu, \{Jian Zhong\}",

note = "Publisher Copyright: {\textcopyright} 2016 Elsevier B.V.",

year = "2017",

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doi = "10.1016/j.snb.2016.07.115",

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TY - JOUR

T1 - Fe NPs and MWCNTs based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids

AU - Wang, Jing

AU - Liu, Xueying

AU - Wang, Yiting

AU - Yu, Lei

AU - Peng, Hui

AU - Zhu, Jian Zhong

PY - 2017/1/1

Y1 - 2017/1/1

N2 - An amperometric electrode based on multiwall carbon nanotubes (MWCNTs) and Fe nanoparticles (NPs) has been successfully fabricated. The electrode combined with Flow Injection Analysis (FIA) exhibits linear response in the concentration range of 0.1–12 μM and the sensitivity of 30.0 nA μM−1 for most of amino acids, confirming good complexation of amino acids (AAs) with Fe NPs on the modified electrode. The determination of 17 amino acids in the hypothalamus microdialysis fluids of guinea pigs, illustrates that it is a powerful tool to investigate physiology and pathology mechanisms.

AB - An amperometric electrode based on multiwall carbon nanotubes (MWCNTs) and Fe nanoparticles (NPs) has been successfully fabricated. The electrode combined with Flow Injection Analysis (FIA) exhibits linear response in the concentration range of 0.1–12 μM and the sensitivity of 30.0 nA μM−1 for most of amino acids, confirming good complexation of amino acids (AAs) with Fe NPs on the modified electrode. The determination of 17 amino acids in the hypothalamus microdialysis fluids of guinea pigs, illustrates that it is a powerful tool to investigate physiology and pathology mechanisms.

KW - Amino acids

KW - Amperometric electrode detector

KW - Fe nanoparticles

KW - Hypothalamus dialysis fluid

KW - Multiwall carbon nanotubes

UR - https://www.scopus.com/pages/publications/84990243340

U2 - 10.1016/j.snb.2016.07.115

DO - 10.1016/j.snb.2016.07.115

M3 - 文章

AN - SCOPUS:84990243340

SN - 0925-4005

VL - 238

SP - 834

EP - 841

JO - Sensors and Actuators B: Chemical

JF - Sensors and Actuators B: Chemical

ER -

Fe NPs and MWCNTs based electrode as FIA detector for determination of amino acids in hypothalamus microdialysis fluids

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Keywords

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