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Facile synthesis of N2-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy

  • Cong Guan
  • , Jian Ji
  • , Zi Li
  • , Qinghua Wei
  • , Xiang Wu
  • , Shunying Liu*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

An efficient one-pot two-step synthetic strategy to access highly selective N2-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N2-substituted-1,2,3-triazole derivatives in good yields.

Original languageEnglish
Article number132670
JournalTetrahedron
Volume108
DOIs
StatePublished - 26 Feb 2022

Keywords

  • 1,2,3-Triazole
  • Facile synthesis
  • One-pot two-step strategy
  • Radical transformation

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