Facile synthesis of N2-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy

Cong Guan; Jian Ji; Zi Li; Qinghua Wei; Xiang Wu; Shunying Liu

doi:10.1016/j.tet.2022.132670

Facile synthesis of N²-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy

Cong Guan, Jian Ji, Zi Li, Qinghua Wei, Xiang Wu, Shunying Liu

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

An efficient one-pot two-step synthetic strategy to access highly selective N²-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N²-substituted-1,2,3-triazole derivatives in good yields.

Original language	English
Article number	132670
Journal	Tetrahedron
Volume	108
DOIs	https://doi.org/10.1016/j.tet.2022.132670
State	Published - 26 Feb 2022

Keywords

1,2,3-Triazole
Facile synthesis
One-pot two-step strategy
Radical transformation

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10.1016/j.tet.2022.132670

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title = "Facile synthesis of N2-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy",

abstract = "An efficient one-pot two-step synthetic strategy to access highly selective N2-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N2-substituted-1,2,3-triazole derivatives in good yields.",

keywords = "1,2,3-Triazole, Facile synthesis, One-pot two-step strategy, Radical transformation",

author = "Cong Guan and Jian Ji and Zi Li and Qinghua Wei and Xiang Wu and Shunying Liu",

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T1 - Facile synthesis of N2-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy

AU - Guan, Cong

AU - Ji, Jian

AU - Li, Zi

AU - Wei, Qinghua

AU - Wu, Xiang

AU - Liu, Shunying

PY - 2022/2/26

Y1 - 2022/2/26

N2 - An efficient one-pot two-step synthetic strategy to access highly selective N2-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N2-substituted-1,2,3-triazole derivatives in good yields.

AB - An efficient one-pot two-step synthetic strategy to access highly selective N2-substituted-1,2,3-triazole from aryl ethynylenes, azides and furan has been developed via a radical transformation. 17 examples of aryl ethynylene with various substituents were converted into their corresponding functionalized N2-substituted-1,2,3-triazole derivatives in good yields.

KW - 1,2,3-Triazole

KW - Facile synthesis

KW - One-pot two-step strategy

KW - Radical transformation

UR - https://www.scopus.com/pages/publications/85124147075

U2 - 10.1016/j.tet.2022.132670

DO - 10.1016/j.tet.2022.132670

M3 - 文章

AN - SCOPUS:85124147075

SN - 0040-4020

VL - 108

JO - Tetrahedron

JF - Tetrahedron

M1 - 132670

ER -

Facile synthesis of N²-substituted-1,2,3-triazole from aryl ethynylene and azide via a one-pot two-step strategy

Abstract

Keywords

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