Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation

Dechao Niu; Xia Wang; Yongsheng Li; Yuanyi Zheng; Faqi Li; Hangrong Chen; Jinlou Gu; Wenru Zhao; Jianlin Shi

doi:10.1002/adma.201204316

Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation

Dechao Niu
, Xia Wang
, Yongsheng Li^*
, Yuanyi Zheng
, Faqi Li
, Hangrong Chen
, Jinlou Gu
, Wenru Zhao
, Jianlin Shi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

100 Scopus citations

Abstract

Multifunctional organic/inorganic hybrid nanovesicles, fabricated by a facile self-assembly/sol-gel approach, display a unique morphology (figure) and satisfactory stability under physiological conditions. By co-encapsulation of superparamagnetic magnetite nanoparticles and a liquid perfluorocarbon, the nanovesicles can be used not only as a dual-modality ultrasound/magnetic resonance contrast agent for accurate cancer diagnosis and monitoring, but also as a therapeutic enhancement agent for effective high-intensity focused ultrasound (HIFU) ablation.

Original language	English
Pages (from-to)	2686-2692
Number of pages	7
Journal	Advanced Materials
Volume	25
Issue number	19
DOIs	https://doi.org/10.1002/adma.201204316
State	Published - 21 May 2013
Externally published	Yes

Keywords

HIFU therapy
magnetic
magnetic resonance imaging
nanoparticles
perfluorocarbons
ultrasound
vesicles

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Niu, D., Wang, X., Li, Y., Zheng, Y., Li, F., Chen, H., Gu, J., Zhao, W., & Shi, J. (2013). Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation. Advanced Materials, 25(19), 2686-2692. https://doi.org/10.1002/adma.201204316

@article{2017e34325f84dd4bc860942b60c4f70,

title = "Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation",

abstract = "Multifunctional organic/inorganic hybrid nanovesicles, fabricated by a facile self-assembly/sol-gel approach, display a unique morphology (figure) and satisfactory stability under physiological conditions. By co-encapsulation of superparamagnetic magnetite nanoparticles and a liquid perfluorocarbon, the nanovesicles can be used not only as a dual-modality ultrasound/magnetic resonance contrast agent for accurate cancer diagnosis and monitoring, but also as a therapeutic enhancement agent for effective high-intensity focused ultrasound (HIFU) ablation.",

keywords = "HIFU therapy, magnetic, magnetic resonance imaging, nanoparticles, perfluorocarbons, ultrasound, vesicles",

author = "Dechao Niu and Xia Wang and Yongsheng Li and Yuanyi Zheng and Faqi Li and Hangrong Chen and Jinlou Gu and Wenru Zhao and Jianlin Shi",

year = "2013",

month = may,

day = "21",

doi = "10.1002/adma.201204316",

language = "英语",

volume = "25",

pages = "2686--2692",

journal = "Advanced Materials",

issn = "0935-9648",

publisher = "Wiley-Blackwell",

number = "19",

}

Niu, D, Wang, X, Li, Y, Zheng, Y, Li, F, Chen, H, Gu, J, Zhao, W & Shi, J 2013, 'Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation', Advanced Materials, vol. 25, no. 19, pp. 2686-2692. https://doi.org/10.1002/adma.201204316

Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation. / Niu, Dechao; Wang, Xia; Li, Yongsheng et al.
In: Advanced Materials, Vol. 25, No. 19, 21.05.2013, p. 2686-2692.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation

AU - Niu, Dechao

AU - Wang, Xia

AU - Li, Yongsheng

AU - Zheng, Yuanyi

AU - Li, Faqi

AU - Chen, Hangrong

AU - Gu, Jinlou

AU - Zhao, Wenru

AU - Shi, Jianlin

PY - 2013/5/21

Y1 - 2013/5/21

N2 - Multifunctional organic/inorganic hybrid nanovesicles, fabricated by a facile self-assembly/sol-gel approach, display a unique morphology (figure) and satisfactory stability under physiological conditions. By co-encapsulation of superparamagnetic magnetite nanoparticles and a liquid perfluorocarbon, the nanovesicles can be used not only as a dual-modality ultrasound/magnetic resonance contrast agent for accurate cancer diagnosis and monitoring, but also as a therapeutic enhancement agent for effective high-intensity focused ultrasound (HIFU) ablation.

AB - Multifunctional organic/inorganic hybrid nanovesicles, fabricated by a facile self-assembly/sol-gel approach, display a unique morphology (figure) and satisfactory stability under physiological conditions. By co-encapsulation of superparamagnetic magnetite nanoparticles and a liquid perfluorocarbon, the nanovesicles can be used not only as a dual-modality ultrasound/magnetic resonance contrast agent for accurate cancer diagnosis and monitoring, but also as a therapeutic enhancement agent for effective high-intensity focused ultrasound (HIFU) ablation.

KW - HIFU therapy

KW - magnetic

KW - magnetic resonance imaging

KW - nanoparticles

KW - perfluorocarbons

KW - ultrasound

KW - vesicles

UR - https://www.scopus.com/pages/publications/84877752301

U2 - 10.1002/adma.201204316

DO - 10.1002/adma.201204316

M3 - 文章

C2 - 23447424

AN - SCOPUS:84877752301

SN - 0935-9648

VL - 25

SP - 2686

EP - 2692

JO - Advanced Materials

JF - Advanced Materials

IS - 19

ER -

Facile synthesis of magnetite/perfluorocarbon Co-loaded organic/inorganic hybrid vesicles for dual-modality ultrasound/magnetic resonance imaging and imaging-guided high-intensity focused ultrasound ablation

Abstract

Keywords

UN SDGs

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