Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique

Chunni Dai; Qingli Li; Jingao Liu; Yiting Wang

doi:10.1109/ICBBE.2010.5515843

Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique

Chunni Dai
, Qingli Li^*
, Jingao Liu
, Yiting Wang

^*Corresponding author for this work

School of Communication and Electronic Engineering

East China Normal University
Guangxi University for Nationalities

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Microscopic hyperspectral imaging technology instead of traditional method is employed to evaluate the therapeutic effects of Erythropoietin (EPO) on diabetic rats. As a relatively new method for biomedical discipline, hyperspectral imaging coupled with microscope can supply not only a variety of dissimilar wavelengths images but also optical spectra at every pixel in these images. With the data cube taken by microscopic pushbroom hyperspectral imager, the spectra of the normal, diabetic, and EPO-treated rats were compared to carry out quantitative analysis. Results show the spectral signature of the EPO group was more similar to that of the Normal than that of the Diabetes to the Normal. The results suggest EPO may prevent cell apoptosis and has protective effect on rat DR at a certain level. Owing to its effective application to the validation of drug efficacy, microscopic hyperspectral imager may probably provide a potential approach for medical researchers in future.

Original language	English
Title of host publication	2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010
DOIs	https://doi.org/10.1109/ICBBE.2010.5515843
State	Published - 2010
Event	4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010 - Chengdu, China Duration: 18 Jun 2010 → 20 Jun 2010

Publication series

Name	2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010

Conference

Conference	4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010
Country/Territory	China
City	Chengdu
Period	18/06/10 → 20/06/10

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Diabetic retinopathy
Erythropoietin
Hyperspectral imaging

Access to Document

10.1109/ICBBE.2010.5515843

Cite this

Dai, C., Li, Q., Liu, J., & Wang, Y. (2010). Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique. In 2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010 Article 5515843 (2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010). https://doi.org/10.1109/ICBBE.2010.5515843

@inproceedings{2a89b5a6d8204c2aa462de6c95d4c923,

title = "Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique",

abstract = "Microscopic hyperspectral imaging technology instead of traditional method is employed to evaluate the therapeutic effects of Erythropoietin (EPO) on diabetic rats. As a relatively new method for biomedical discipline, hyperspectral imaging coupled with microscope can supply not only a variety of dissimilar wavelengths images but also optical spectra at every pixel in these images. With the data cube taken by microscopic pushbroom hyperspectral imager, the spectra of the normal, diabetic, and EPO-treated rats were compared to carry out quantitative analysis. Results show the spectral signature of the EPO group was more similar to that of the Normal than that of the Diabetes to the Normal. The results suggest EPO may prevent cell apoptosis and has protective effect on rat DR at a certain level. Owing to its effective application to the validation of drug efficacy, microscopic hyperspectral imager may probably provide a potential approach for medical researchers in future.",

keywords = "Diabetic retinopathy, Erythropoietin, Hyperspectral imaging",

author = "Chunni Dai and Qingli Li and Jingao Liu and Yiting Wang",

year = "2010",

doi = "10.1109/ICBBE.2010.5515843",

language = "英语",

isbn = "9781424447138",

series = "2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010",

booktitle = "2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010",

note = "4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010 ; Conference date: 18-06-2010 Through 20-06-2010",

}

Dai, C, Li, Q, Liu, J & Wang, Y 2010, Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique. in 2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010., 5515843, 2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010, 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010, Chengdu, China, 18/06/10. https://doi.org/10.1109/ICBBE.2010.5515843

Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique. / Dai, Chunni; Li, Qingli; Liu, Jingao et al.
2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010. 2010. 5515843 (2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique

AU - Dai, Chunni

AU - Li, Qingli

AU - Liu, Jingao

AU - Wang, Yiting

PY - 2010

Y1 - 2010

N2 - Microscopic hyperspectral imaging technology instead of traditional method is employed to evaluate the therapeutic effects of Erythropoietin (EPO) on diabetic rats. As a relatively new method for biomedical discipline, hyperspectral imaging coupled with microscope can supply not only a variety of dissimilar wavelengths images but also optical spectra at every pixel in these images. With the data cube taken by microscopic pushbroom hyperspectral imager, the spectra of the normal, diabetic, and EPO-treated rats were compared to carry out quantitative analysis. Results show the spectral signature of the EPO group was more similar to that of the Normal than that of the Diabetes to the Normal. The results suggest EPO may prevent cell apoptosis and has protective effect on rat DR at a certain level. Owing to its effective application to the validation of drug efficacy, microscopic hyperspectral imager may probably provide a potential approach for medical researchers in future.

AB - Microscopic hyperspectral imaging technology instead of traditional method is employed to evaluate the therapeutic effects of Erythropoietin (EPO) on diabetic rats. As a relatively new method for biomedical discipline, hyperspectral imaging coupled with microscope can supply not only a variety of dissimilar wavelengths images but also optical spectra at every pixel in these images. With the data cube taken by microscopic pushbroom hyperspectral imager, the spectra of the normal, diabetic, and EPO-treated rats were compared to carry out quantitative analysis. Results show the spectral signature of the EPO group was more similar to that of the Normal than that of the Diabetes to the Normal. The results suggest EPO may prevent cell apoptosis and has protective effect on rat DR at a certain level. Owing to its effective application to the validation of drug efficacy, microscopic hyperspectral imager may probably provide a potential approach for medical researchers in future.

KW - Diabetic retinopathy

KW - Erythropoietin

KW - Hyperspectral imaging

UR - https://www.scopus.com/pages/publications/77956148556

U2 - 10.1109/ICBBE.2010.5515843

DO - 10.1109/ICBBE.2010.5515843

M3 - 会议稿件

AN - SCOPUS:77956148556

SN - 9781424447138

T3 - 2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010

BT - 2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010

T2 - 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010

Y2 - 18 June 2010 through 20 June 2010

ER -

Dai C, Li Q, Liu J, Wang Y. Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique. In 2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010. 2010. 5515843. (2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010). doi: 10.1109/ICBBE.2010.5515843

Evaluation of erythropoietin efficacy on diabetic rats based on microscopic hyperspectral imaging technique

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this