Enhanced translocation of poly(dt)45 through an α-hemolysin nanopore by binding with antibody

Yi Lun Ying, Da Wei Li, Yang Li, Jeremy S. Lee, Yi Tao Long

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

The translocation time of poly(dT)45 through an α-hemolysin pore was reduced in the presence of a DNA-binding Fab fragment. The Fab acts as a rudder to steer the DNA into the pore.

Original languageEnglish
Pages (from-to)5690-5692
Number of pages3
JournalChemical Communications
Volume47
Issue number20
DOIs
StatePublished - 3 May 2011
Externally publishedYes

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