Engine-Trailer-Structured Nanotrucks for Efficient Nano-Bio Interactions and Bioimaging-Guided Drug Delivery

Wenxing Wang; Peiyuan Wang; Liang Chen; Mengyao Zhao; Chin Te Hung; Chengzhong Yu; Areej Abdulkareem Al-Khalaf; Wael N. Hozzein; Fan Zhang; Xiaomin Li; Dongyuan Zhao

doi:10.1016/j.chempr.2020.01.010

Engine-Trailer-Structured Nanotrucks for Efficient Nano-Bio Interactions and Bioimaging-Guided Drug Delivery

Wenxing Wang
, Peiyuan Wang
, Liang Chen
, Mengyao Zhao
, Chin Te Hung
, Chengzhong Yu
, Areej Abdulkareem Al-Khalaf
, Wael N. Hozzein
, Fan Zhang
, Xiaomin Li^*
, Dongyuan Zhao

^*Corresponding author for this work

Fudan University
University of Queensland
Princess Nourah Bint Abdulrahman University
King Saud University
Beni-Suef University

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

We have rationally fabricated an asymmetric structured mesoporous nanotruck by the interfacial-energy-mediated anisotropic growth strategy. This nanotruck possesses distinguished dual domains: (1) spherical SiO₂ head with a rough surface as an engine for enhanced nano-bio interactions and (2) a periodic mesoporous organosilica nanorod with high surface area as a trailer for efficient drug loading. The nanotrucks can be further functionalized by embedding functional nanoparticles in the rough heads and exhibit great potentials in biomedicine.

Original language	English
Pages (from-to)	1097-1112
Number of pages	16
Journal	Chem
Volume	6
Issue number	5
DOIs	https://doi.org/10.1016/j.chempr.2020.01.010
State	Published - 14 May 2020
Externally published	Yes

Keywords

SDG3: Good health and well-being
asymmetric nanomaterials
drug delivery
mesoporous silica
rough surfaces

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10.1016/j.chempr.2020.01.010

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@article{5553dd89b05d4378a17e8cf3558543f2,

title = "Engine-Trailer-Structured Nanotrucks for Efficient Nano-Bio Interactions and Bioimaging-Guided Drug Delivery",

abstract = "We have rationally fabricated an asymmetric structured mesoporous nanotruck by the interfacial-energy-mediated anisotropic growth strategy. This nanotruck possesses distinguished dual domains: (1) spherical SiO2 head with a rough surface as an engine for enhanced nano-bio interactions and (2) a periodic mesoporous organosilica nanorod with high surface area as a trailer for efficient drug loading. The nanotrucks can be further functionalized by embedding functional nanoparticles in the rough heads and exhibit great potentials in biomedicine.",

keywords = "SDG3: Good health and well-being, asymmetric nanomaterials, drug delivery, mesoporous silica, rough surfaces",

author = "Wenxing Wang and Peiyuan Wang and Liang Chen and Mengyao Zhao and Hung, \{Chin Te\} and Chengzhong Yu and Al-Khalaf, \{Areej Abdulkareem\} and Hozzein, \{Wael N.\} and Fan Zhang and Xiaomin Li and Dongyuan Zhao",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Inc.",

year = "2020",

month = may,

day = "14",

doi = "10.1016/j.chempr.2020.01.010",

language = "英语",

volume = "6",

pages = "1097--1112",

journal = "Chem",

issn = "2451-9308",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Engine-Trailer-Structured Nanotrucks for Efficient Nano-Bio Interactions and Bioimaging-Guided Drug Delivery

AU - Wang, Wenxing

AU - Wang, Peiyuan

AU - Chen, Liang

AU - Zhao, Mengyao

AU - Hung, Chin Te

AU - Yu, Chengzhong

AU - Al-Khalaf, Areej Abdulkareem

AU - Hozzein, Wael N.

AU - Zhang, Fan

AU - Li, Xiaomin

AU - Zhao, Dongyuan

PY - 2020/5/14

Y1 - 2020/5/14

N2 - We have rationally fabricated an asymmetric structured mesoporous nanotruck by the interfacial-energy-mediated anisotropic growth strategy. This nanotruck possesses distinguished dual domains: (1) spherical SiO2 head with a rough surface as an engine for enhanced nano-bio interactions and (2) a periodic mesoporous organosilica nanorod with high surface area as a trailer for efficient drug loading. The nanotrucks can be further functionalized by embedding functional nanoparticles in the rough heads and exhibit great potentials in biomedicine.

AB - We have rationally fabricated an asymmetric structured mesoporous nanotruck by the interfacial-energy-mediated anisotropic growth strategy. This nanotruck possesses distinguished dual domains: (1) spherical SiO2 head with a rough surface as an engine for enhanced nano-bio interactions and (2) a periodic mesoporous organosilica nanorod with high surface area as a trailer for efficient drug loading. The nanotrucks can be further functionalized by embedding functional nanoparticles in the rough heads and exhibit great potentials in biomedicine.

KW - SDG3: Good health and well-being

KW - asymmetric nanomaterials

KW - drug delivery

KW - mesoporous silica

KW - rough surfaces

UR - https://www.scopus.com/pages/publications/85084357539

U2 - 10.1016/j.chempr.2020.01.010

DO - 10.1016/j.chempr.2020.01.010

M3 - 文章

AN - SCOPUS:85084357539

SN - 2451-9308

VL - 6

SP - 1097

EP - 1112

JO - Chem

JF - Chem

IS - 5

ER -

Engine-Trailer-Structured Nanotrucks for Efficient Nano-Bio Interactions and Bioimaging-Guided Drug Delivery

Abstract

Keywords

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