Encapsulation of CdSe/ZnSe quantum dots by liposome complexes

Gui Ye Shan; Di Li; Li Yun Feng; Xiang Gui Kong; Yi Chun Liu; Yu Bai Bai; Tie Jin Li; Jia Zhong Sun

doi:10.1002/cjoc.200591688

Encapsulation of CdSe/ZnSe quantum dots by liposome complexes

Gui Ye Shan^*
, Di Li
, Li Yun Feng
, Xiang Gui Kong
, Yi Chun Liu
, Yu Bai Bai
, Tie Jin Li
, Jia Zhong Sun

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

A general method was developed to encapsulate CdSe/ZnSe quantum dots by phospholipids liposome complexes, which rendered the quantum dots water-soluble and biocompatible. The encapsulation process was confirmed by transmission electron microscopy and photoluminescence spectroscopy. The photoluminescence of CdSe/ZnSe quantum dots in the liposome complexes was quite stable; their fluorescence remained in the same order of magnitude even after 90 min of photobleaching. CdSe/ZnSe quantum dots in the liposome complexes were further applied as fluorescence marker in immune assay for the detection of rat monoclonal CD95 antibodies. Quantum dots encapsulated by this facile strategy could also be applied in DNA, enzyme and cell labeling, and contribute a lot to the development of in vivo imaging and probing of tissues.

Original language	English
Pages (from-to)	1688-1692
Number of pages	5
Journal	Chinese Journal of Chemistry
Volume	23
Issue number	12
DOIs	https://doi.org/10.1002/cjoc.200591688
State	Published - Dec 2005
Externally published	Yes

Keywords

Immunoassay
Liposome
Quantum dot

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title = "Encapsulation of CdSe/ZnSe quantum dots by liposome complexes",

abstract = "A general method was developed to encapsulate CdSe/ZnSe quantum dots by phospholipids liposome complexes, which rendered the quantum dots water-soluble and biocompatible. The encapsulation process was confirmed by transmission electron microscopy and photoluminescence spectroscopy. The photoluminescence of CdSe/ZnSe quantum dots in the liposome complexes was quite stable; their fluorescence remained in the same order of magnitude even after 90 min of photobleaching. CdSe/ZnSe quantum dots in the liposome complexes were further applied as fluorescence marker in immune assay for the detection of rat monoclonal CD95 antibodies. Quantum dots encapsulated by this facile strategy could also be applied in DNA, enzyme and cell labeling, and contribute a lot to the development of in vivo imaging and probing of tissues.",

keywords = "Immunoassay, Liposome, Quantum dot",

author = "Shan, \{Gui Ye\} and Di Li and Feng, \{Li Yun\} and Kong, \{Xiang Gui\} and Liu, \{Yi Chun\} and Bai, \{Yu Bai\} and Li, \{Tie Jin\} and Sun, \{Jia Zhong\}",

year = "2005",

month = dec,

doi = "10.1002/cjoc.200591688",

language = "英语",

volume = "23",

pages = "1688--1692",

journal = "Chinese Journal of Chemistry",

issn = "1001-604X",

publisher = "John Wiley and Sons Inc",

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TY - JOUR

T1 - Encapsulation of CdSe/ZnSe quantum dots by liposome complexes

AU - Shan, Gui Ye

AU - Li, Di

AU - Feng, Li Yun

AU - Kong, Xiang Gui

AU - Liu, Yi Chun

AU - Bai, Yu Bai

AU - Li, Tie Jin

AU - Sun, Jia Zhong

PY - 2005/12

Y1 - 2005/12

N2 - A general method was developed to encapsulate CdSe/ZnSe quantum dots by phospholipids liposome complexes, which rendered the quantum dots water-soluble and biocompatible. The encapsulation process was confirmed by transmission electron microscopy and photoluminescence spectroscopy. The photoluminescence of CdSe/ZnSe quantum dots in the liposome complexes was quite stable; their fluorescence remained in the same order of magnitude even after 90 min of photobleaching. CdSe/ZnSe quantum dots in the liposome complexes were further applied as fluorescence marker in immune assay for the detection of rat monoclonal CD95 antibodies. Quantum dots encapsulated by this facile strategy could also be applied in DNA, enzyme and cell labeling, and contribute a lot to the development of in vivo imaging and probing of tissues.

AB - A general method was developed to encapsulate CdSe/ZnSe quantum dots by phospholipids liposome complexes, which rendered the quantum dots water-soluble and biocompatible. The encapsulation process was confirmed by transmission electron microscopy and photoluminescence spectroscopy. The photoluminescence of CdSe/ZnSe quantum dots in the liposome complexes was quite stable; their fluorescence remained in the same order of magnitude even after 90 min of photobleaching. CdSe/ZnSe quantum dots in the liposome complexes were further applied as fluorescence marker in immune assay for the detection of rat monoclonal CD95 antibodies. Quantum dots encapsulated by this facile strategy could also be applied in DNA, enzyme and cell labeling, and contribute a lot to the development of in vivo imaging and probing of tissues.

KW - Immunoassay

KW - Liposome

KW - Quantum dot

UR - https://www.scopus.com/pages/publications/30744439563

U2 - 10.1002/cjoc.200591688

DO - 10.1002/cjoc.200591688

M3 - 文章

AN - SCOPUS:30744439563

SN - 1001-604X

VL - 23

SP - 1688

EP - 1692

JO - Chinese Journal of Chemistry

JF - Chinese Journal of Chemistry

IS - 12

ER -

Encapsulation of CdSe/ZnSe quantum dots by liposome complexes

Abstract

Keywords

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