Enantioselective organocatalytic conjugate addition of nitroalkanes to electrophilic 2-iminochromenes

Wenjun Li; Hui Liu; Xuefeng Jiang; Jian Wang

doi:10.1021/cs300313j

Enantioselective organocatalytic conjugate addition of nitroalkanes to electrophilic 2-iminochromenes

Wenjun Li
, Hui Liu
, Xuefeng Jiang^*
, Jian Wang

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

48 Scopus citations

Abstract

We disclose a new efficient enantioselective organocatalytic conjugate addition method for the preparation of 2-amino-4H-chromenes in high to excellent yields (75-95%) and with high to excellent enantioselectivities (86-97% ee). It is noteworthy that the 2-iminochromene was first disclosed as an active electrophile.

Original language	English
Pages (from-to)	1535-1538
Number of pages	4
Journal	ACS Catalysis
Volume	2
Issue number	8
DOIs	https://doi.org/10.1021/cs300313j
State	Published - 3 Aug 2012

Keywords

2-amino-4H-chromenes
conjugate addition
nitroalkane
organocatalysis

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10.1021/cs300313j

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title = "Enantioselective organocatalytic conjugate addition of nitroalkanes to electrophilic 2-iminochromenes",

abstract = "We disclose a new efficient enantioselective organocatalytic conjugate addition method for the preparation of 2-amino-4H-chromenes in high to excellent yields (75-95\%) and with high to excellent enantioselectivities (86-97\% ee). It is noteworthy that the 2-iminochromene was first disclosed as an active electrophile.",

keywords = "2-amino-4H-chromenes, conjugate addition, nitroalkane, organocatalysis",

author = "Wenjun Li and Hui Liu and Xuefeng Jiang and Jian Wang",

year = "2012",

month = aug,

day = "3",

doi = "10.1021/cs300313j",

language = "英语",

volume = "2",

pages = "1535--1538",

journal = "ACS Catalysis",

issn = "2155-5435",

publisher = "American Chemical Society",

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TY - JOUR

T1 - Enantioselective organocatalytic conjugate addition of nitroalkanes to electrophilic 2-iminochromenes

AU - Li, Wenjun

AU - Liu, Hui

AU - Jiang, Xuefeng

AU - Wang, Jian

PY - 2012/8/3

Y1 - 2012/8/3

N2 - We disclose a new efficient enantioselective organocatalytic conjugate addition method for the preparation of 2-amino-4H-chromenes in high to excellent yields (75-95%) and with high to excellent enantioselectivities (86-97% ee). It is noteworthy that the 2-iminochromene was first disclosed as an active electrophile.

AB - We disclose a new efficient enantioselective organocatalytic conjugate addition method for the preparation of 2-amino-4H-chromenes in high to excellent yields (75-95%) and with high to excellent enantioselectivities (86-97% ee). It is noteworthy that the 2-iminochromene was first disclosed as an active electrophile.

KW - 2-amino-4H-chromenes

KW - conjugate addition

KW - nitroalkane

KW - organocatalysis

UR - https://www.scopus.com/pages/publications/84864580567

U2 - 10.1021/cs300313j

DO - 10.1021/cs300313j

M3 - 文章

AN - SCOPUS:84864580567

SN - 2155-5435

VL - 2

SP - 1535

EP - 1538

JO - ACS Catalysis

JF - ACS Catalysis

IS - 8

ER -

Enantioselective organocatalytic conjugate addition of nitroalkanes to electrophilic 2-iminochromenes

Abstract

Keywords

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