Electrochemically Promoted Asymmetric Transfer Hydrogenation of 2,2,2-Trifluoroacetophenone

Huan Wang; Ying Na Yue; Rui Xiong; Yu Ting Liu; Li Rong Yang; Ying Wang; Jia Xing Lu

doi:10.1021/acs.joc.1c01030

Electrochemically Promoted Asymmetric Transfer Hydrogenation of 2,2,2-Trifluoroacetophenone

Huan Wang^*
, Ying Na Yue
, Rui Xiong
, Yu Ting Liu
, Li Rong Yang
, Ying Wang
, Jia Xing Lu^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The study reported an electrochemically promoted asymmetric hydrogen transfer reaction of 2,2,2-trifluoroacetophenone with a chiral Ru complex. (R)-α-(Trifluoromethyl) benzyl alcohol with a 96% yield and 94% ee could be obtained with only a 0.5 F mol^-1charge amount at room temperature and normal pressure.

Original language	English
Pages (from-to)	16158-16161
Number of pages	4
Journal	Journal of Organic Chemistry
Volume	86
Issue number	22
DOIs	https://doi.org/10.1021/acs.joc.1c01030
State	Published - 19 Nov 2021

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title = "Electrochemically Promoted Asymmetric Transfer Hydrogenation of 2,2,2-Trifluoroacetophenone",

abstract = "The study reported an electrochemically promoted asymmetric hydrogen transfer reaction of 2,2,2-trifluoroacetophenone with a chiral Ru complex. (R)-α-(Trifluoromethyl) benzyl alcohol with a 96\% yield and 94\% ee could be obtained with only a 0.5 F mol-1charge amount at room temperature and normal pressure.",

author = "Huan Wang and Yue, \{Ying Na\} and Rui Xiong and Liu, \{Yu Ting\} and Yang, \{Li Rong\} and Ying Wang and Lu, \{Jia Xing\}",

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doi = "10.1021/acs.joc.1c01030",

language = "英语",

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TY - JOUR

T1 - Electrochemically Promoted Asymmetric Transfer Hydrogenation of 2,2,2-Trifluoroacetophenone

AU - Wang, Huan

AU - Yue, Ying Na

AU - Xiong, Rui

AU - Liu, Yu Ting

AU - Yang, Li Rong

AU - Wang, Ying

AU - Lu, Jia Xing

PY - 2021/11/19

Y1 - 2021/11/19

N2 - The study reported an electrochemically promoted asymmetric hydrogen transfer reaction of 2,2,2-trifluoroacetophenone with a chiral Ru complex. (R)-α-(Trifluoromethyl) benzyl alcohol with a 96% yield and 94% ee could be obtained with only a 0.5 F mol-1charge amount at room temperature and normal pressure.

AB - The study reported an electrochemically promoted asymmetric hydrogen transfer reaction of 2,2,2-trifluoroacetophenone with a chiral Ru complex. (R)-α-(Trifluoromethyl) benzyl alcohol with a 96% yield and 94% ee could be obtained with only a 0.5 F mol-1charge amount at room temperature and normal pressure.

UR - https://www.scopus.com/pages/publications/85113904092

U2 - 10.1021/acs.joc.1c01030

DO - 10.1021/acs.joc.1c01030

M3 - 文章

AN - SCOPUS:85113904092

SN - 0022-3263

VL - 86

SP - 16158

EP - 16161

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 22

ER -

Electrochemically Promoted Asymmetric Transfer Hydrogenation of 2,2,2-Trifluoroacetophenone

Abstract

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