Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: From principle to applications in living cells

Yongping Luo; Yang Tian; Qi Rui

doi:10.1039/b902150g

Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO₂ nanoneedles: From principle to applications in living cells

Yongping Luo, Yang Tian^*, Qi Rui

^*Corresponding author for this work

Tongji University

Research output: Contribution to journal › Article › peer-review

56 Scopus citations

Abstract

A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O₂^-) based on direct electron transfer of a biomimetic superoxide dismutase (SOD), Mn ₃(PO₄)₂, at highly conductive TiO₂ nanoneedles is reported for the first time, and is further exploited for the determination of O₂^- from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O ₂^- might be proposed as a biomarker of cancer.

Original language	English
Pages (from-to)	3014-3016
Number of pages	3
Journal	Chemical Communications
Issue number	21
DOIs	https://doi.org/10.1039/b902150g
State	Published - 2009
Externally published	Yes

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10.1039/b902150g

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title = "Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO2 nanoneedles: From principle to applications in living cells",

abstract = "A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O2-) based on direct electron transfer of a biomimetic superoxide dismutase (SOD), Mn 3(PO4)2, at highly conductive TiO2 nanoneedles is reported for the first time, and is further exploited for the determination of O2- from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O 2- might be proposed as a biomarker of cancer.",

author = "Yongping Luo and Yang Tian and Qi Rui",

year = "2009",

doi = "10.1039/b902150g",

language = "英语",

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journal = "Chemical Communications",

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publisher = "Royal Society of Chemistry",

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T2 - From principle to applications in living cells

AU - Luo, Yongping

AU - Tian, Yang

AU - Rui, Qi

PY - 2009

Y1 - 2009

N2 - A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O2-) based on direct electron transfer of a biomimetic superoxide dismutase (SOD), Mn 3(PO4)2, at highly conductive TiO2 nanoneedles is reported for the first time, and is further exploited for the determination of O2- from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O 2- might be proposed as a biomarker of cancer.

AB - A novel strategy for extremely durable, reliable, and selective in situ real-time determination of superoxide anion (O2-) based on direct electron transfer of a biomimetic superoxide dismutase (SOD), Mn 3(PO4)2, at highly conductive TiO2 nanoneedles is reported for the first time, and is further exploited for the determination of O2- from living normal and cancer ovary cells directly adhered onto the modified surface, suggesting that O 2- might be proposed as a biomarker of cancer.

UR - https://www.scopus.com/pages/publications/65949093290

U2 - 10.1039/b902150g

DO - 10.1039/b902150g

M3 - 文章

C2 - 19462071

AN - SCOPUS:65949093290

SN - 1359-7345

SP - 3014

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JO - Chemical Communications

JF - Chemical Communications

IS - 21

ER -

Electrochemical assay of superoxide based on biomimetic enzyme at highly conductive TiO₂ nanoneedles: From principle to applications in living cells

Abstract

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