Electric field directed layer-by-layer assembly of horseradish peroxidase nanotubes via anodic aluminum oxide template

Fanghua Wu, Zhichao Hu, Liwei Wang, Jingjing Xu, Yuezhong Xian, Yuan Tian, Litong Jin

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

A novel method based on electric field directed layer-by-layer assembly (EFDLA) and template synthesis is successfully developed to fabricate horseradish peroxidase (HRP) nanotubes. It provides a rapid and general strategy for functional protein nanoarrays. The alternative deposition of poly(diallyldimethylammonium chloride) (PDDA) and HRP are characterized by SEM, TEM, UV-vis and electrochemical impedance spectroscopy (EIS). Moreover, the UV-vis spectrometry and electrochemistry of HRP indicate that immobilization of PDDA/HRP via EFDLA coupled with template synthesis could retain the conformations and bioactivities of HRP.

Original languageEnglish
Pages (from-to)630-634
Number of pages5
JournalElectrochemistry Communications
Volume10
Issue number4
DOIs
StatePublished - Apr 2008

Keywords

  • Anodic aluminum oxide
  • Direct electrochemistry
  • Horseradish peroxidase
  • Layer-by-layer assembly
  • Nanotubes

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