Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions

Lin Qiu; Xin Guo; Chaoqun Ma; Huang Qiu; Shunying Liu; Liping Yang; Wenhao Hu

doi:10.1039/c3cc49063g

Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions

Lin Qiu
, Xin Guo
, Chaoqun Ma
, Huang Qiu
, Shunying Liu^*
, Liping Yang
, Wenhao Hu

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

29 Scopus citations

Abstract

Four-component Mannich reactions subsequently followed by an intramolecular oxo-Michael addition were developed to efficiently produce chiral cyclic acetals with high diastereoselectivity and enantioselectivity.

Original language	English
Pages (from-to)	2196-2198
Number of pages	3
Journal	Chemical Communications
Volume	50
Issue number	17
DOIs	https://doi.org/10.1039/c3cc49063g
State	Published - 30 Jan 2014

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@article{40e0a25e010e477080ac85b92b8ab92f,

title = "Efficient synthesis of chiral cyclic acetals by metal and Br{\o}nsted acid co-catalyzed enantioselective four-component cascade reactions",

abstract = "Four-component Mannich reactions subsequently followed by an intramolecular oxo-Michael addition were developed to efficiently produce chiral cyclic acetals with high diastereoselectivity and enantioselectivity.",

author = "Lin Qiu and Xin Guo and Chaoqun Ma and Huang Qiu and Shunying Liu and Liping Yang and Wenhao Hu",

year = "2014",

month = jan,

day = "30",

doi = "10.1039/c3cc49063g",

language = "英语",

volume = "50",

pages = "2196--2198",

journal = "Chemical Communications",

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TY - JOUR

T1 - Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions

AU - Qiu, Lin

AU - Guo, Xin

AU - Ma, Chaoqun

AU - Qiu, Huang

AU - Liu, Shunying

AU - Yang, Liping

AU - Hu, Wenhao

PY - 2014/1/30

Y1 - 2014/1/30

N2 - Four-component Mannich reactions subsequently followed by an intramolecular oxo-Michael addition were developed to efficiently produce chiral cyclic acetals with high diastereoselectivity and enantioselectivity.

AB - Four-component Mannich reactions subsequently followed by an intramolecular oxo-Michael addition were developed to efficiently produce chiral cyclic acetals with high diastereoselectivity and enantioselectivity.

UR - https://www.scopus.com/pages/publications/84893505829

U2 - 10.1039/c3cc49063g

DO - 10.1039/c3cc49063g

M3 - 文章

C2 - 24430986

AN - SCOPUS:84893505829

SN - 1359-7345

VL - 50

SP - 2196

EP - 2198

JO - Chemical Communications

JF - Chemical Communications

IS - 17

ER -

Efficient synthesis of chiral cyclic acetals by metal and Brønsted acid co-catalyzed enantioselective four-component cascade reactions

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