Efficient synthesis of benzosultams containing continuous quaternary carbons via trapping active ylides with cyclic N-sulfonyl ketimines

Zhengli Luo; Xuwen Chen; Jian Xue; Yaqi Deng; Suzhen Dong; Shunying Liu

doi:10.1039/d2qo01409b

Efficient synthesis of benzosultams containing continuous quaternary carbons via trapping active ylides with cyclic N-sulfonyl ketimines

Zhengli Luo
, Xuwen Chen
, Jian Xue
, Yaqi Deng
, Suzhen Dong^*
, Shunying Liu^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A rapid and efficient method for the synthesis of benzosultams containing continuous quaternary carbons in a one pot fashion has been developed with moderate to excellent yields at room temperature under air. The resulting products exhibit good anticancer activity in osteosarcoma cells.

Original language	English
Pages (from-to)	6592-6597
Number of pages	6
Journal	Organic Chemistry Frontiers
Volume	9
Issue number	23
DOIs	https://doi.org/10.1039/d2qo01409b
State	Published - 13 Oct 2022

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title = "Efficient synthesis of benzosultams containing continuous quaternary carbons via trapping active ylides with cyclic N-sulfonyl ketimines",

abstract = "A rapid and efficient method for the synthesis of benzosultams containing continuous quaternary carbons in a one pot fashion has been developed with moderate to excellent yields at room temperature under air. The resulting products exhibit good anticancer activity in osteosarcoma cells.",

author = "Zhengli Luo and Xuwen Chen and Jian Xue and Yaqi Deng and Suzhen Dong and Shunying Liu",

note = "Publisher Copyright: {\textcopyright} 2022 The Royal Society of Chemistry.",

year = "2022",

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day = "13",

doi = "10.1039/d2qo01409b",

language = "英语",

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TY - JOUR

T1 - Efficient synthesis of benzosultams containing continuous quaternary carbons via trapping active ylides with cyclic N-sulfonyl ketimines

AU - Luo, Zhengli

AU - Chen, Xuwen

AU - Xue, Jian

AU - Deng, Yaqi

AU - Dong, Suzhen

AU - Liu, Shunying

PY - 2022/10/13

Y1 - 2022/10/13

N2 - A rapid and efficient method for the synthesis of benzosultams containing continuous quaternary carbons in a one pot fashion has been developed with moderate to excellent yields at room temperature under air. The resulting products exhibit good anticancer activity in osteosarcoma cells.

AB - A rapid and efficient method for the synthesis of benzosultams containing continuous quaternary carbons in a one pot fashion has been developed with moderate to excellent yields at room temperature under air. The resulting products exhibit good anticancer activity in osteosarcoma cells.

UR - https://www.scopus.com/pages/publications/85141721580

U2 - 10.1039/d2qo01409b

DO - 10.1039/d2qo01409b

M3 - 文章

AN - SCOPUS:85141721580

SN - 2052-4110

VL - 9

SP - 6592

EP - 6597

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

IS - 23

ER -

Efficient synthesis of benzosultams containing continuous quaternary carbons via trapping active ylides with cyclic N-sulfonyl ketimines

Abstract

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