dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls

Qiongwen Kang; Yan Wang; Zongkang Wang; Nana Fei; Peng He; Lingkai Kong; Yanzhong Li

doi:10.1039/d4qo00016a

dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls

Qiongwen Kang, Yan Wang, Zongkang Wang, Nana Fei, Peng He, Lingkai Kong, Yanzhong Li

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

A dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls under mild conditions has been developed. The desired products were obtained in high to excellent yields. A mechanism involving the formation of the key intermediate 3-indolol-2-carboxamide, which originates from an indolyl dimer intermediate is proposed. The notable advantages of this process include good functional group tolerance, excellent yields, and operational simplicity.

Original language	English
Journal	Organic Chemistry Frontiers
DOIs	https://doi.org/10.1039/d4qo00016a
State	Accepted/In press - 2024

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title = "dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls",

abstract = "A dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls under mild conditions has been developed. The desired products were obtained in high to excellent yields. A mechanism involving the formation of the key intermediate 3-indolol-2-carboxamide, which originates from an indolyl dimer intermediate is proposed. The notable advantages of this process include good functional group tolerance, excellent yields, and operational simplicity.",

author = "Qiongwen Kang and Yan Wang and Zongkang Wang and Nana Fei and Peng He and Lingkai Kong and Yanzhong Li",

note = "Publisher Copyright: {\textcopyright} 2024 The Royal Society of Chemistry.",

year = "2024",

doi = "10.1039/d4qo00016a",

language = "英语",

journal = "Organic Chemistry Frontiers",

issn = "2052-4110",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls

AU - Kang, Qiongwen

AU - Wang, Yan

AU - Wang, Zongkang

AU - Fei, Nana

AU - He, Peng

AU - Kong, Lingkai

AU - Li, Yanzhong

PY - 2024

Y1 - 2024

N2 - A dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls under mild conditions has been developed. The desired products were obtained in high to excellent yields. A mechanism involving the formation of the key intermediate 3-indolol-2-carboxamide, which originates from an indolyl dimer intermediate is proposed. The notable advantages of this process include good functional group tolerance, excellent yields, and operational simplicity.

AB - A dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls under mild conditions has been developed. The desired products were obtained in high to excellent yields. A mechanism involving the formation of the key intermediate 3-indolol-2-carboxamide, which originates from an indolyl dimer intermediate is proposed. The notable advantages of this process include good functional group tolerance, excellent yields, and operational simplicity.

UR - https://www.scopus.com/pages/publications/85186464644

U2 - 10.1039/d4qo00016a

DO - 10.1039/d4qo00016a

M3 - 文章

AN - SCOPUS:85186464644

SN - 2052-4110

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

ER -

dppb and TfOH promoted cascade reaction of o-nitrophenylpropiolamides to access C2-spiro-pseudoindoxyls

Abstract

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