@inproceedings{8695866237ce44dba964295d18f81c9e,
title = "Distributed gene clinical decision support system based on cloud computing",
abstract = "The clinical decision support system can effectively solve the limitations of doctors' knowledge, reduce misdiagnosis and help enhance health. The traditional genetic data storage and analysis technology based on the stand-alone environment have limited scalability, which has been difficult to meet the computational requirements of rapid genetic data growth. In this paper, we propose a distributed gene clinical decision support system, which is named as GCDSS. We implemented a prototype based on cloud computing. To speed up the data processing of GCDSS, we present a novel distributed read mapping algorithm CloudBWA that leverages batch processing strategy to map reads on Apache Spark. Evaluations show that GCDSS and its component CloudBWA achieve outstanding performance and excellent scalability. Compared with distributed algorithms, CloudBWA achieves up to 2.63 times speedup over SparkBWA.",
keywords = "Alluxio, Cloud computing, Gene Clinical Decision Support System, Genetic data analysis, Read mapping, Spark",
author = "Bo Xu and Changlong Li and Hang Zhuang and Jiali Wang and Qingfeng Wang and Chao Wang and Xuehai Zhou",
note = "Publisher Copyright: {\textcopyright} 2017 IEEE.; 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017 ; Conference date: 13-11-2017 Through 16-11-2017",
year = "2017",
month = dec,
day = "15",
doi = "10.1109/BIBM.2017.8217695",
language = "英语",
series = "Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "485--490",
editor = "Illhoi Yoo and Zheng, \{Jane Huiru\} and Yang Gong and Hu, \{Xiaohua Tony\} and Chi-Ren Shyu and Yana Bromberg and Jean Gao and Dmitry Korkin",
booktitle = "Proceedings - 2017 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2017",
address = "美国",
}