Direct measurement of nitric oxide release from the rat hippocampus

Yuezhong Xian; Wen Zhang; Jian Xue; Xiangyang Ying; Litong Jin

doi:10.1016/S0003-2670(00)00863-1

Direct measurement of nitric oxide release from the rat hippocampus

Yuezhong Xian, Wen Zhang, Jian Xue, Xiangyang Ying, Litong Jin

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

A novel, sensitive, selective and reproducible nitric oxide (NO) microsensor is developed for direct measurement of NO in vitro and in vivo. Using the microsensor, the first direct measurements NO release from the rat hippocampus are made. NO levels are increased by stimulated with L-arginine and acetylcholine. L-N(ω)-nitro-arginine, a NO synthase inhibitor, decreases the NO increase induced by L-arginine and acetylcholine. The effect of sodium nitroprusside, a NO donor, is also performed. Copyright (C) 2000 Elsevier Science B.V.

Original language	English
Pages (from-to)	127-133
Number of pages	7
Journal	Analytica Chimica Acta
Volume	415
Issue number	1-2
DOIs	https://doi.org/10.1016/S0003-2670(00)00863-1
State	Published - 30 Jun 2000

Keywords

Hippocampus
Microsensor
Nitric oxide

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10.1016/S0003-2670(00)00863-1

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abstract = "A novel, sensitive, selective and reproducible nitric oxide (NO) microsensor is developed for direct measurement of NO in vitro and in vivo. Using the microsensor, the first direct measurements NO release from the rat hippocampus are made. NO levels are increased by stimulated with L-arginine and acetylcholine. L-N(ω)-nitro-arginine, a NO synthase inhibitor, decreases the NO increase induced by L-arginine and acetylcholine. The effect of sodium nitroprusside, a NO donor, is also performed. Copyright (C) 2000 Elsevier Science B.V.",

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T1 - Direct measurement of nitric oxide release from the rat hippocampus

AU - Xian, Yuezhong

AU - Zhang, Wen

AU - Xue, Jian

AU - Ying, Xiangyang

AU - Jin, Litong

PY - 2000/6/30

Y1 - 2000/6/30

N2 - A novel, sensitive, selective and reproducible nitric oxide (NO) microsensor is developed for direct measurement of NO in vitro and in vivo. Using the microsensor, the first direct measurements NO release from the rat hippocampus are made. NO levels are increased by stimulated with L-arginine and acetylcholine. L-N(ω)-nitro-arginine, a NO synthase inhibitor, decreases the NO increase induced by L-arginine and acetylcholine. The effect of sodium nitroprusside, a NO donor, is also performed. Copyright (C) 2000 Elsevier Science B.V.

AB - A novel, sensitive, selective and reproducible nitric oxide (NO) microsensor is developed for direct measurement of NO in vitro and in vivo. Using the microsensor, the first direct measurements NO release from the rat hippocampus are made. NO levels are increased by stimulated with L-arginine and acetylcholine. L-N(ω)-nitro-arginine, a NO synthase inhibitor, decreases the NO increase induced by L-arginine and acetylcholine. The effect of sodium nitroprusside, a NO donor, is also performed. Copyright (C) 2000 Elsevier Science B.V.

KW - Hippocampus

KW - Microsensor

KW - Nitric oxide

UR - https://www.scopus.com/pages/publications/0034733860

U2 - 10.1016/S0003-2670(00)00863-1

DO - 10.1016/S0003-2670(00)00863-1

M3 - 文章

AN - SCOPUS:0034733860

SN - 0003-2670

VL - 415

SP - 127

EP - 133

JO - Analytica Chimica Acta

JF - Analytica Chimica Acta

IS - 1-2

ER -

Direct measurement of nitric oxide release from the rat hippocampus

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Keywords

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