Diffusion tensor imaging for predicting hand motor outcome in chronic stroke patients

F. Song; F. Zhang; D. Z. Yin; Yong Shan Hu; Ming Xia Fan; H. H. Ni; X. L. Nan; X. Cui; C. X. Zhou; C. S. Huang; Q. Zhao; L. H. Ma; Y. M. Xu; Q. J. Xia

doi:10.1177/147323001204000113

Diffusion tensor imaging for predicting hand motor outcome in chronic stroke patients

F. Song, F. Zhang, D. Z. Yin, Yong Shan Hu, Ming Xia Fan, H. H. Ni, X. L. Nan, X. Cui, C. X. Zhou, C. S. Huang, Q. Zhao, L. H. Ma, Y. M. Xu, Q. J. Xia

School of Psychology and Cognitive Science

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Objective: Previous studies have indicated that diffusion tensor imaging (DTI) values are related to clinical outcome in stroke patients. This prospective study explored whether DTI values were predictive for hand function outcome in chronic stroke patients. Methods: The DTI parameters (rλ₁, rλ₂₃, fractional anisotropy [rFA] and mean diffusivity [rMD]) were investigated in patients with completely paralysed hands (CPH; n = 10) or partially paralysed hands (PPH; n = 10), by two methods of analysis: segment of the corticospinal tract [sCST] analysis; pure region of interest [ROI] analysis. Spearman's correlation coefficient was used to assess the correlation between the DTI parameters and the following clinical measures: Fugl-Meyer Assessment [FMA]; National Institutes of Health Stroke Scale [NIHSS]. Results: Significant differences were found between CPH and PPH for rFA and rλ₂₃ (sCST analysis) and for rMD and rλ₂₃ (ROI analysis). The rλ₂₃ (sCST analysis) correlated with the NIHSS; the rMD (sCST analysis) correlated with the FMA (hand). Conclusion: The three parameters, rFA, rλ₂₃ and rMD may have predictive value for evaluating hand function outcome in chronic stroke patients.

Original language	English
Pages (from-to)	126-133
Number of pages	8
Journal	Journal of International Medical Research
Volume	40
Issue number	1
DOIs	https://doi.org/10.1177/147323001204000113
State	Published - Feb 2012

Keywords

Diffusion tensor imaging (DTI)
Hand function outcome
Pure region of interest (ROI) analysis
Segment of the corticospinal tract (SCST) analysis
Stroke

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10.1177/147323001204000113

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@article{4ec89b1727f34f3698d4bf620704da36,

title = "Diffusion tensor imaging for predicting hand motor outcome in chronic stroke patients",

abstract = "Objective: Previous studies have indicated that diffusion tensor imaging (DTI) values are related to clinical outcome in stroke patients. This prospective study explored whether DTI values were predictive for hand function outcome in chronic stroke patients. Methods: The DTI parameters (rλ1, rλ23, fractional anisotropy [rFA] and mean diffusivity [rMD]) were investigated in patients with completely paralysed hands (CPH; n = 10) or partially paralysed hands (PPH; n = 10), by two methods of analysis: segment of the corticospinal tract [sCST] analysis; pure region of interest [ROI] analysis. Spearman's correlation coefficient was used to assess the correlation between the DTI parameters and the following clinical measures: Fugl-Meyer Assessment [FMA]; National Institutes of Health Stroke Scale [NIHSS]. Results: Significant differences were found between CPH and PPH for rFA and rλ23 (sCST analysis) and for rMD and rλ23 (ROI analysis). The rλ23 (sCST analysis) correlated with the NIHSS; the rMD (sCST analysis) correlated with the FMA (hand). Conclusion: The three parameters, rFA, rλ23 and rMD may have predictive value for evaluating hand function outcome in chronic stroke patients.",

keywords = "Diffusion tensor imaging (DTI), Hand function outcome, Pure region of interest (ROI) analysis, Segment of the corticospinal tract (SCST) analysis, Stroke",

author = "F. Song and F. Zhang and Yin, \{D. Z.\} and Hu, \{Yong Shan\} and Fan, \{Ming Xia\} and Ni, \{H. H.\} and Nan, \{X. L.\} and X. Cui and Zhou, \{C. X.\} and Huang, \{C. S.\} and Q. Zhao and Ma, \{L. H.\} and Xu, \{Y. M.\} and Xia, \{Q. J.\}",

year = "2012",

month = feb,

doi = "10.1177/147323001204000113",

language = "英语",

volume = "40",

pages = "126--133",

journal = "Journal of International Medical Research",

issn = "0300-0605",

publisher = "SAGE Publications Ltd",

number = "1",

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TY - JOUR

T1 - Diffusion tensor imaging for predicting hand motor outcome in chronic stroke patients

AU - Song, F.

AU - Zhang, F.

AU - Yin, D. Z.

AU - Hu, Yong Shan

AU - Fan, Ming Xia

AU - Ni, H. H.

AU - Nan, X. L.

AU - Cui, X.

AU - Zhou, C. X.

AU - Huang, C. S.

AU - Zhao, Q.

AU - Ma, L. H.

AU - Xu, Y. M.

AU - Xia, Q. J.

PY - 2012/2

Y1 - 2012/2

N2 - Objective: Previous studies have indicated that diffusion tensor imaging (DTI) values are related to clinical outcome in stroke patients. This prospective study explored whether DTI values were predictive for hand function outcome in chronic stroke patients. Methods: The DTI parameters (rλ1, rλ23, fractional anisotropy [rFA] and mean diffusivity [rMD]) were investigated in patients with completely paralysed hands (CPH; n = 10) or partially paralysed hands (PPH; n = 10), by two methods of analysis: segment of the corticospinal tract [sCST] analysis; pure region of interest [ROI] analysis. Spearman's correlation coefficient was used to assess the correlation between the DTI parameters and the following clinical measures: Fugl-Meyer Assessment [FMA]; National Institutes of Health Stroke Scale [NIHSS]. Results: Significant differences were found between CPH and PPH for rFA and rλ23 (sCST analysis) and for rMD and rλ23 (ROI analysis). The rλ23 (sCST analysis) correlated with the NIHSS; the rMD (sCST analysis) correlated with the FMA (hand). Conclusion: The three parameters, rFA, rλ23 and rMD may have predictive value for evaluating hand function outcome in chronic stroke patients.

AB - Objective: Previous studies have indicated that diffusion tensor imaging (DTI) values are related to clinical outcome in stroke patients. This prospective study explored whether DTI values were predictive for hand function outcome in chronic stroke patients. Methods: The DTI parameters (rλ1, rλ23, fractional anisotropy [rFA] and mean diffusivity [rMD]) were investigated in patients with completely paralysed hands (CPH; n = 10) or partially paralysed hands (PPH; n = 10), by two methods of analysis: segment of the corticospinal tract [sCST] analysis; pure region of interest [ROI] analysis. Spearman's correlation coefficient was used to assess the correlation between the DTI parameters and the following clinical measures: Fugl-Meyer Assessment [FMA]; National Institutes of Health Stroke Scale [NIHSS]. Results: Significant differences were found between CPH and PPH for rFA and rλ23 (sCST analysis) and for rMD and rλ23 (ROI analysis). The rλ23 (sCST analysis) correlated with the NIHSS; the rMD (sCST analysis) correlated with the FMA (hand). Conclusion: The three parameters, rFA, rλ23 and rMD may have predictive value for evaluating hand function outcome in chronic stroke patients.

KW - Diffusion tensor imaging (DTI)

KW - Hand function outcome

KW - Pure region of interest (ROI) analysis

KW - Segment of the corticospinal tract (SCST) analysis

KW - Stroke

UR - https://www.scopus.com/pages/publications/84863295624

U2 - 10.1177/147323001204000113

DO - 10.1177/147323001204000113

M3 - 文章

C2 - 22429352

AN - SCOPUS:84863295624

SN - 0300-0605

VL - 40

SP - 126

EP - 133

JO - Journal of International Medical Research

JF - Journal of International Medical Research

IS - 1

ER -

Diffusion tensor imaging for predicting hand motor outcome in chronic stroke patients

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