Development of cell microarray by using superhydrophilic silicon dioxide nano structure

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Studies on cellular behaviors on substrates with various physicochemical properties have important implications in cytology and bio-medical field. And a variety of cell microarrays have been developed to study in vitro. Our study aims to explore the relations between nano silicon dioxide structure substrates and circulating tumor cells (CTCs) adhesion, and create cell microarrays based on the cell adhesions with the substrate. The method for the preparation of microarray presented herein is based on creating a superhydrophilic array by DRIE technology and thermal oxidation. Superhydrophilic microarrays were achieved as a convex array on SOI wafer. The extreme wettability of the superhydrophilic arrays guaranteed an easy and homogeneous adsorption of the cells, while flat silicon dioxide barriers effectively prevented cross-contamination of the cells.

Original languageEnglish
Title of host publication16th International Conference on Nanotechnology - IEEE NANO 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages238-240
Number of pages3
ISBN (Electronic)9781509039142
DOIs
StatePublished - 21 Nov 2016
Externally publishedYes
Event16th IEEE International Conference on Nanotechnology - IEEE NANO 2016 - Sendai, Japan
Duration: 22 Aug 201625 Aug 2016

Publication series

Name16th International Conference on Nanotechnology - IEEE NANO 2016

Conference

Conference16th IEEE International Conference on Nanotechnology - IEEE NANO 2016
Country/TerritoryJapan
CitySendai
Period22/08/1625/08/16

Keywords

  • Cell microarray
  • Superhydrophilic
  • Wettability

Fingerprint

Dive into the research topics of 'Development of cell microarray by using superhydrophilic silicon dioxide nano structure'. Together they form a unique fingerprint.

Cite this