Developing an ionic medium for ligandless-palladium-catalysed Suzuki and Heck couplings

Gang Zou, Zhiyong Wang, Junru Zhu, Jie Tang, Ming Y. He

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

High-melting-point alkylammonium tetrafluoroborates melt with water or toluene to form biphasic mixtures at much lower temperatures than their normal melting points, thus could serve as green reaction media for Suzuki and Heck couplings. Advantages of using the aqueous-ammonium biphasic catalytic system include: (1) working well with a ligandless palladium catalyst, (2) solving the solubility problem of organic substrates and (3) simplifying work-up procedures for both separation of products and recycling of reaction media.

Original languageEnglish
Pages (from-to)193-198
Number of pages6
JournalJournal of Molecular Catalysis A: Chemical
Volume206
Issue number1-2
DOIs
StatePublished - 1 Oct 2003

Keywords

  • Biphasic catalysis
  • Heck-coupling
  • Ligandless-catalyst
  • Molten salt
  • Suzuki-coupling

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