Design and synthesis of new Imatinib analogs containing thiazolyl moiety

Yu Luo; Haiyan Liu; Wei Lu

doi:10.1002/jhet.1055

Design and synthesis of new Imatinib analogs containing thiazolyl moiety

Yu Luo
, Haiyan Liu
, Wei Lu

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.

Original language	English
Pages (from-to)	1357-1362
Number of pages	6
Journal	Journal of Heterocyclic Chemistry
Volume	50
Issue number	6
DOIs	https://doi.org/10.1002/jhet.1055
State	Published - Nov 2013

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/jhet.1055

Cite this

@article{53776801abca41c88ce5419fc18f385d,

title = "Design and synthesis of new Imatinib analogs containing thiazolyl moiety",

abstract = "A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.",

author = "Yu Luo and Haiyan Liu and Wei Lu",

year = "2013",

month = nov,

doi = "10.1002/jhet.1055",

language = "英语",

volume = "50",

pages = "1357--1362",

journal = "Journal of Heterocyclic Chemistry",

issn = "0022-152X",

publisher = "John Wiley and Sons Inc",

number = "6",

}

TY - JOUR

T1 - Design and synthesis of new Imatinib analogs containing thiazolyl moiety

AU - Luo, Yu

AU - Liu, Haiyan

AU - Lu, Wei

PY - 2013/11

Y1 - 2013/11

N2 - A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.

AB - A series of thiazolyl moiety-containing pyrimidine derivatives were synthesized and evaluated for their cytotoxicity against chronic myelogenous leukemia cell line K562 and human breast cancer cell line MCF-7. Most compounds showed good antiproliferation activity.

UR - https://www.scopus.com/pages/publications/84888642289

U2 - 10.1002/jhet.1055

DO - 10.1002/jhet.1055

M3 - 文章

AN - SCOPUS:84888642289

SN - 0022-152X

VL - 50

SP - 1357

EP - 1362

JO - Journal of Heterocyclic Chemistry

JF - Journal of Heterocyclic Chemistry

IS - 6

ER -

Design and synthesis of new Imatinib analogs containing thiazolyl moiety

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this