Design and synthesis of a biotin-tagged photoaffinity probe of paeoniflorin

  • Wen Wei Qiu
  • , Jie Xu
  • , Da Zhi Liu
  • , Jing Ya Li
  • , Yang Ye
  • , Xing Zu Zhu
  • , Jia Li*
  • , Fa Jun Nan
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

A trifunctional probe (binding element-photoreactive group-affinity tag) of natural product paeoniflorin was designed and synthesized based on the previous primary structure-activity relationship. This new probe is a potential tool for labeling, purification, and identification of the target proteins.

Original languageEnglish
Pages (from-to)3306-3309
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume16
Issue number12
DOIs
StatePublished - 15 Jun 2006
Externally publishedYes

Keywords

  • Paeoniflorin
  • Photoaffinity probe
  • Synthesis

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