Dearomative Iodocyclization of N-(o-Alkynyl)aryl Isoindole

Zhiqiong Tang; Fang Zhang; Tengfei Yao; Xun Shen Liu; Yuanyuan Liu; Lu Liu

doi:10.1021/acs.joc.2c00424

Dearomative Iodocyclization of N-(o-Alkynyl)aryl Isoindole

Zhiqiong Tang
, Fang Zhang
, Tengfei Yao
, Xun Shen Liu
, Yuanyuan Liu
, Lu Liu^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We present a dearomative iodocyclization of N-(o-alkynyl)aryl isoindole here, which affords various biologically active benzoindoleazine skeletons containing alkenyl iodine. The products can further undergo cycloaddition or coupling reactions to afford a series of highly functionalized N-fused polycyclic scaffolds.

Original language	English
Pages (from-to)	7531-7535
Number of pages	5
Journal	Journal of Organic Chemistry
Volume	87
Issue number	11
DOIs	https://doi.org/10.1021/acs.joc.2c00424
State	Published - 3 Jun 2022

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title = "Dearomative Iodocyclization of N-(o-Alkynyl)aryl Isoindole",

abstract = "We present a dearomative iodocyclization of N-(o-alkynyl)aryl isoindole here, which affords various biologically active benzoindoleazine skeletons containing alkenyl iodine. The products can further undergo cycloaddition or coupling reactions to afford a series of highly functionalized N-fused polycyclic scaffolds.",

author = "Zhiqiong Tang and Fang Zhang and Tengfei Yao and Liu, \{Xun Shen\} and Yuanyuan Liu and Lu Liu",

year = "2022",

month = jun,

day = "3",

doi = "10.1021/acs.joc.2c00424",

language = "英语",

volume = "87",

pages = "7531--7535",

journal = "Journal of Organic Chemistry",

issn = "0022-3263",

publisher = "American Chemical Society",

number = "11",

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TY - JOUR

T1 - Dearomative Iodocyclization of N-(o-Alkynyl)aryl Isoindole

AU - Tang, Zhiqiong

AU - Zhang, Fang

AU - Yao, Tengfei

AU - Liu, Xun Shen

AU - Liu, Yuanyuan

AU - Liu, Lu

PY - 2022/6/3

Y1 - 2022/6/3

N2 - We present a dearomative iodocyclization of N-(o-alkynyl)aryl isoindole here, which affords various biologically active benzoindoleazine skeletons containing alkenyl iodine. The products can further undergo cycloaddition or coupling reactions to afford a series of highly functionalized N-fused polycyclic scaffolds.

AB - We present a dearomative iodocyclization of N-(o-alkynyl)aryl isoindole here, which affords various biologically active benzoindoleazine skeletons containing alkenyl iodine. The products can further undergo cycloaddition or coupling reactions to afford a series of highly functionalized N-fused polycyclic scaffolds.

UR - https://www.scopus.com/pages/publications/85131434070

U2 - 10.1021/acs.joc.2c00424

DO - 10.1021/acs.joc.2c00424

M3 - 文章

AN - SCOPUS:85131434070

SN - 0022-3263

VL - 87

SP - 7531

EP - 7535

JO - Journal of Organic Chemistry

JF - Journal of Organic Chemistry

IS - 11

ER -

Dearomative Iodocyclization of N-(o-Alkynyl)aryl Isoindole

Abstract

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