DCPO based nanoparticles as a near-infrared fluorescent probe for Cathepsin B

Bin Bao; Yaqian Liu; Lei Wang; Wei Lu

doi:10.1039/c6ra14628g

DCPO based nanoparticles as a near-infrared fluorescent probe for Cathepsin B

Bin Bao
, Yaqian Liu
, Lei Wang
, Wei Lu^*

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University
Dalian University of Technology

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

A novel NIR fluorescent probe for CTB was designed and synthesized based on DCPO. The newly synthesized probe was quite water-soluble and formed nanoparticles which has potential in tumor-targeted imaging. When treated with CTB, the probe released the fluorescent molecule DCPO. Imaging of different tumor cells also indicated that the probe was efficient in detecting CTB.

Original language	English
Pages (from-to)	69540-69545
Number of pages	6
Journal	RSC Advances
Volume	6
Issue number	73
DOIs	https://doi.org/10.1039/c6ra14628g
State	Published - 2016

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10.1039/c6ra14628g

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@article{2045d801074f4f47a102b49211b5d60a,

title = "DCPO based nanoparticles as a near-infrared fluorescent probe for Cathepsin B",

abstract = "A novel NIR fluorescent probe for CTB was designed and synthesized based on DCPO. The newly synthesized probe was quite water-soluble and formed nanoparticles which has potential in tumor-targeted imaging. When treated with CTB, the probe released the fluorescent molecule DCPO. Imaging of different tumor cells also indicated that the probe was efficient in detecting CTB.",

author = "Bin Bao and Yaqian Liu and Lei Wang and Wei Lu",

note = "Publisher Copyright: {\textcopyright} 2016 The Royal Society of Chemistry.",

year = "2016",

doi = "10.1039/c6ra14628g",

language = "英语",

volume = "6",

pages = "69540--69545",

journal = "RSC Advances",

issn = "2046-2069",

publisher = "Royal Society of Chemistry",

number = "73",

}

TY - JOUR

T1 - DCPO based nanoparticles as a near-infrared fluorescent probe for Cathepsin B

AU - Bao, Bin

AU - Liu, Yaqian

AU - Wang, Lei

AU - Lu, Wei

PY - 2016

Y1 - 2016

N2 - A novel NIR fluorescent probe for CTB was designed and synthesized based on DCPO. The newly synthesized probe was quite water-soluble and formed nanoparticles which has potential in tumor-targeted imaging. When treated with CTB, the probe released the fluorescent molecule DCPO. Imaging of different tumor cells also indicated that the probe was efficient in detecting CTB.

AB - A novel NIR fluorescent probe for CTB was designed and synthesized based on DCPO. The newly synthesized probe was quite water-soluble and formed nanoparticles which has potential in tumor-targeted imaging. When treated with CTB, the probe released the fluorescent molecule DCPO. Imaging of different tumor cells also indicated that the probe was efficient in detecting CTB.

UR - https://www.scopus.com/pages/publications/84979924897

U2 - 10.1039/c6ra14628g

DO - 10.1039/c6ra14628g

M3 - 文章

AN - SCOPUS:84979924897

SN - 2046-2069

VL - 6

SP - 69540

EP - 69545

JO - RSC Advances

JF - RSC Advances

IS - 73

ER -

DCPO based nanoparticles as a near-infrared fluorescent probe for Cathepsin B

Abstract

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