Dark-field microscopy in imaging of plasmon resonant nanoparticles

Mengmeng Liu; Jie Chao; Suhui Deng; Kun Wang; Kun Li; Chunhai Fan

doi:10.1016/j.colsurfb.2014.06.001

Dark-field microscopy in imaging of plasmon resonant nanoparticles

Mengmeng Liu
, Jie Chao
, Suhui Deng^*
, Kun Wang
, Kun Li
, Chunhai Fan

^*Corresponding author for this work

Chinese Academy of Sciences

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

Dark-field microscopy (DFM) and spectroscopy base on localized surface plasmon resonance (LSPR) have been widely applied in biological sensing and single-molecule imaging. Using plasmonic nanoparticles with controlled geometrical, optical, and surface chemical properties as the probes, the scattering light depending on the surrounding environment can be detected by DF microscope. Signal-to-noise radio and time resolution of the conventional DFM is not sufficient to identify single molecular dynamics. To break these limitations, significant improvements have been made in recent years. This critical review is focused on the developments of the DFM and the utilization of DFM as a powerful technology in the application of LSPR detection.

Original language	English
Pages (from-to)	111-117
Number of pages	7
Journal	Colloids and Surfaces B: Biointerfaces
Volume	124
DOIs	https://doi.org/10.1016/j.colsurfb.2014.06.001
State	Published - 1 Dec 2014
Externally published	Yes

Keywords

Dark-field microscopy (DFM)
Localized surface plasmon resonance (LSPR)
Plasmonic nanoparticles

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10.1016/j.colsurfb.2014.06.001

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title = "Dark-field microscopy in imaging of plasmon resonant nanoparticles",

abstract = "Dark-field microscopy (DFM) and spectroscopy base on localized surface plasmon resonance (LSPR) have been widely applied in biological sensing and single-molecule imaging. Using plasmonic nanoparticles with controlled geometrical, optical, and surface chemical properties as the probes, the scattering light depending on the surrounding environment can be detected by DF microscope. Signal-to-noise radio and time resolution of the conventional DFM is not sufficient to identify single molecular dynamics. To break these limitations, significant improvements have been made in recent years. This critical review is focused on the developments of the DFM and the utilization of DFM as a powerful technology in the application of LSPR detection.",

keywords = "Dark-field microscopy (DFM), Localized surface plasmon resonance (LSPR), Plasmonic nanoparticles",

author = "Mengmeng Liu and Jie Chao and Suhui Deng and Kun Wang and Kun Li and Chunhai Fan",

note = "Publisher Copyright: {\textcopyright} 2014 Elsevier B.V.",

year = "2014",

month = dec,

day = "1",

doi = "10.1016/j.colsurfb.2014.06.001",

language = "英语",

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journal = "Colloids and Surfaces B: Biointerfaces",

issn = "0927-7765",

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TY - JOUR

T1 - Dark-field microscopy in imaging of plasmon resonant nanoparticles

AU - Liu, Mengmeng

AU - Chao, Jie

AU - Deng, Suhui

AU - Wang, Kun

AU - Li, Kun

AU - Fan, Chunhai

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Dark-field microscopy (DFM) and spectroscopy base on localized surface plasmon resonance (LSPR) have been widely applied in biological sensing and single-molecule imaging. Using plasmonic nanoparticles with controlled geometrical, optical, and surface chemical properties as the probes, the scattering light depending on the surrounding environment can be detected by DF microscope. Signal-to-noise radio and time resolution of the conventional DFM is not sufficient to identify single molecular dynamics. To break these limitations, significant improvements have been made in recent years. This critical review is focused on the developments of the DFM and the utilization of DFM as a powerful technology in the application of LSPR detection.

AB - Dark-field microscopy (DFM) and spectroscopy base on localized surface plasmon resonance (LSPR) have been widely applied in biological sensing and single-molecule imaging. Using plasmonic nanoparticles with controlled geometrical, optical, and surface chemical properties as the probes, the scattering light depending on the surrounding environment can be detected by DF microscope. Signal-to-noise radio and time resolution of the conventional DFM is not sufficient to identify single molecular dynamics. To break these limitations, significant improvements have been made in recent years. This critical review is focused on the developments of the DFM and the utilization of DFM as a powerful technology in the application of LSPR detection.

KW - Dark-field microscopy (DFM)

KW - Localized surface plasmon resonance (LSPR)

KW - Plasmonic nanoparticles

UR - https://www.scopus.com/pages/publications/85027945569

U2 - 10.1016/j.colsurfb.2014.06.001

DO - 10.1016/j.colsurfb.2014.06.001

M3 - 文章

AN - SCOPUS:85027945569

SN - 0927-7765

VL - 124

SP - 111

EP - 117

JO - Colloids and Surfaces B: Biointerfaces

JF - Colloids and Surfaces B: Biointerfaces

ER -

Dark-field microscopy in imaging of plasmon resonant nanoparticles

Abstract

Keywords

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