Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery

Prasanna Lakshmi Abbaraju; Yannan Yang; Meihua Yu; Jianye Fu; Chun Xu; Chengzhong Yu

doi:10.1002/asia.201700392

Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery

Prasanna Lakshmi Abbaraju
, Yannan Yang
, Meihua Yu
, Jianye Fu
, Chun Xu
, Chengzhong Yu^*

^*Corresponding author for this work

University of Queensland

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Multifunctional core–shell-structured dendritic mesoporous silica nanoparticles with a fullerene-doped silica core, a dendritic silica shell and large pores have been prepared. The combination of photodynamic therapy and antibody therapeutics significantly inhibits the cancer cell growth by effectively reducing the level of anti-apoptotic proteins.

Original language	English
Pages (from-to)	1465-1469
Number of pages	5
Journal	Chemistry - An Asian Journal
Volume	12
Issue number	13
DOIs	https://doi.org/10.1002/asia.201700392
State	Published - 4 Jul 2017
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

anti-apoptotic proteins
antibody therapeutics
fullerenes
mesoporous silica nanoparticles
photodynamic therapy

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10.1002/asia.201700392

Cite this

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title = "Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery",

abstract = "Multifunctional core–shell-structured dendritic mesoporous silica nanoparticles with a fullerene-doped silica core, a dendritic silica shell and large pores have been prepared. The combination of photodynamic therapy and antibody therapeutics significantly inhibits the cancer cell growth by effectively reducing the level of anti-apoptotic proteins.",

keywords = "anti-apoptotic proteins, antibody therapeutics, fullerenes, mesoporous silica nanoparticles, photodynamic therapy",

author = "Abbaraju, \{Prasanna Lakshmi\} and Yannan Yang and Meihua Yu and Jianye Fu and Chun Xu and Chengzhong Yu",

note = "Publisher Copyright: {\textcopyright} 2017 Wiley-VCH Verlag GmbH \& Co. KGaA, Weinheim",

year = "2017",

month = jul,

day = "4",

doi = "10.1002/asia.201700392",

language = "英语",

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pages = "1465--1469",

journal = "Chemistry - An Asian Journal",

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}

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T1 - Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery

AU - Abbaraju, Prasanna Lakshmi

AU - Yang, Yannan

AU - Yu, Meihua

AU - Fu, Jianye

AU - Xu, Chun

AU - Yu, Chengzhong

PY - 2017/7/4

Y1 - 2017/7/4

N2 - Multifunctional core–shell-structured dendritic mesoporous silica nanoparticles with a fullerene-doped silica core, a dendritic silica shell and large pores have been prepared. The combination of photodynamic therapy and antibody therapeutics significantly inhibits the cancer cell growth by effectively reducing the level of anti-apoptotic proteins.

AB - Multifunctional core–shell-structured dendritic mesoporous silica nanoparticles with a fullerene-doped silica core, a dendritic silica shell and large pores have been prepared. The combination of photodynamic therapy and antibody therapeutics significantly inhibits the cancer cell growth by effectively reducing the level of anti-apoptotic proteins.

KW - anti-apoptotic proteins

KW - antibody therapeutics

KW - fullerenes

KW - mesoporous silica nanoparticles

KW - photodynamic therapy

UR - https://www.scopus.com/pages/publications/85021087346

U2 - 10.1002/asia.201700392

DO - 10.1002/asia.201700392

M3 - 文章

C2 - 28481442

AN - SCOPUS:85021087346

SN - 1861-4728

VL - 12

SP - 1465

EP - 1469

JO - Chemistry - An Asian Journal

JF - Chemistry - An Asian Journal

IS - 13

ER -

Core–Shell-structured Dendritic Mesoporous Silica Nanoparticles for Combined Photodynamic Therapy and Antibody Delivery

Abstract

UN SDGs

Keywords

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