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Copper-promoted probe for nitric oxide based on o-phenylenediamine: Large blue-shift in absorption and fluorescence enhancement

  • Xiaolong Sun
  • , Yufang Xu
  • , Weiping Zhu
  • , Chunsheng He
  • , Lin Xu
  • , Youjun Yang
  • , Xuhong Qian*
  • *Corresponding author for this work
  • East China University of Science and Technology

Research output: Contribution to journalArticlepeer-review

Abstract

We developed a new o-phenylenediamine-based compound as a turn-on fluorescent probe for nitric oxide (NO) with a large blue shift in absorption. It showed high selectivity and sensitivity toward nitric oxide over other ROS and RNS species in neutral buffer solution. The analytical detection limit (ADL) was 30 nM. As far as we are aware this is the first o-phenylenediamine-based NO probe using Cu 2+ as a promoter.

Original languageEnglish
Pages (from-to)919-922
Number of pages4
JournalAnalytical Methods
Volume4
Issue number4
DOIs
StatePublished - Apr 2012
Externally publishedYes

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