TY - JOUR
T1 - Copper-catalyzed synthesis of five-membered heterocycles via double C-N bond formation
T2 - an efficient synthesis of pyrroles, dihydropyrroles, and carbazoles
AU - Li, Ende
AU - Xu, Xiaobing
AU - Li, Hongfeng
AU - Zhang, Huimin
AU - Xu, Xiaolei
AU - Yuan, Xiyuan
AU - Li, Yanzhong
PY - 2009/10/31
Y1 - 2009/10/31
N2 - An efficient copper-catalyzed double C-N bond forming reaction using diiodides and nitrogen-centered nucleophiles including amides and carbamates is reported. The reactions proceed to afford di- or tri-substituted N-acylpyrroles, dihydropyrroles, and carbazoles in good to excellent yields when different diiodides such as 1,4-diiodo-1,3-butadienes, 1,4-dihalobut-1-enes, and 2,2′-diiodobiphenyls were employed, respectively. It is crucial to use CuI as the catalyst with the assistance of proper base and diamine ligand.
AB - An efficient copper-catalyzed double C-N bond forming reaction using diiodides and nitrogen-centered nucleophiles including amides and carbamates is reported. The reactions proceed to afford di- or tri-substituted N-acylpyrroles, dihydropyrroles, and carbazoles in good to excellent yields when different diiodides such as 1,4-diiodo-1,3-butadienes, 1,4-dihalobut-1-enes, and 2,2′-diiodobiphenyls were employed, respectively. It is crucial to use CuI as the catalyst with the assistance of proper base and diamine ligand.
UR - https://www.scopus.com/pages/publications/70349320317
U2 - 10.1016/j.tet.2009.08.075
DO - 10.1016/j.tet.2009.08.075
M3 - 文章
AN - SCOPUS:70349320317
SN - 0040-4020
VL - 65
SP - 8961
EP - 8968
JO - Tetrahedron
JF - Tetrahedron
IS - 44
ER -