TY - GEN
T1 - Clinically Interpretable Geometric Constraints for Optic Cup and Disc Segmentation
AU - Qin, Rui
AU - Zhao, Bailiang
AU - Yang, Kuo
AU - Wu, Yue
AU - Gao, Peng
AU - Hu, Menghan
N1 - Publisher Copyright:
© 2025 IEEE.
PY - 2025
Y1 - 2025
N2 - We present GCN-CIS, a segmentation framework that embeds clinically interpretable geometric constraints into deep networks for optic cup and disc delineation in fundus images. A Prior Boundary Attention Module (PBAM) sharpens boundary predictions, while an ISNT-guided geometric loss enforces anatomically plausible regional ordering. Evaluated on an internal glaucoma screening set and three public benchmarks (REFUGE, ORIGA, Drishti-GS), GCN-CIS yields consistent gains in cup/disc Dice and reduces vCDR error compared to strong baselines. The method improves clinical reliability of segmentation outputs and facilitates efficient vCDR estimation for screening workflows. Code will be released.
AB - We present GCN-CIS, a segmentation framework that embeds clinically interpretable geometric constraints into deep networks for optic cup and disc delineation in fundus images. A Prior Boundary Attention Module (PBAM) sharpens boundary predictions, while an ISNT-guided geometric loss enforces anatomically plausible regional ordering. Evaluated on an internal glaucoma screening set and three public benchmarks (REFUGE, ORIGA, Drishti-GS), GCN-CIS yields consistent gains in cup/disc Dice and reduces vCDR error compared to strong baselines. The method improves clinical reliability of segmentation outputs and facilitates efficient vCDR estimation for screening workflows. Code will be released.
KW - Boundary-Aware Attention
KW - Clinically Oriented Segmentation
KW - Geometrically Constrained Interpretable Model
KW - ISNT-Guided Loss Function
UR - https://www.scopus.com/pages/publications/105033546665
U2 - 10.1109/BIBM66473.2025.11356105
DO - 10.1109/BIBM66473.2025.11356105
M3 - 会议稿件
AN - SCOPUS:105033546665
T3 - Proceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
SP - 1805
EP - 1808
BT - Proceedings - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
A2 - Liu, Juan
A2 - Huang, Jingshan
A2 - Wang, Xiaowo
A2 - Zhang, Fa
A2 - Zou, Xiufen
A2 - Tian, Tian
A2 - Hu, Xiaohua
A2 - Hu, Bin
A2 - Xiong, Yi
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2025 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2025
Y2 - 15 December 2025 through 18 December 2025
ER -