Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

Shun Ying Liu; Lei Fang; Yong Bing He; Wing Hong Chan; Kai Tai Yeung; Yuen Kit Cheng; Rong Hua Yang

doi:10.1021/ol052341t

Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

Shun Ying Liu, Lei Fang, Yong Bing He, Wing Hong Chan, Kai Tai Yeung, Yuen Kit Cheng, Rong Hua Yang

Research output: Contribution to journal › Article › peer-review

131 Scopus citations

Abstract

(Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH₃OH/H₂O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 ⁶.

Original language	English
Pages (from-to)	5825-5828
Number of pages	4
Journal	Organic Letters
Volume	7
Issue number	26
DOIs	https://doi.org/10.1021/ol052341t
State	Published - 22 Dec 2005
Externally published	Yes

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title = "Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions",

abstract = "(Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 6.",

author = "Liu, \{Shun Ying\} and Lei Fang and He, \{Yong Bing\} and Chan, \{Wing Hong\} and Yeung, \{Kai Tai\} and Cheng, \{Yuen Kit\} and Yang, \{Rong Hua\}",

year = "2005",

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day = "22",

doi = "10.1021/ol052341t",

language = "英语",

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journal = "Organic Letters",

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TY - JOUR

T1 - Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

AU - Liu, Shun Ying

AU - Fang, Lei

AU - He, Yong Bing

AU - Chan, Wing Hong

AU - Yeung, Kai Tai

AU - Cheng, Yuen Kit

AU - Yang, Rong Hua

PY - 2005/12/22

Y1 - 2005/12/22

N2 - (Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 6.

AB - (Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 6.

UR - https://www.scopus.com/pages/publications/30144436966

U2 - 10.1021/ol052341t

DO - 10.1021/ol052341t

M3 - 文章

C2 - 16354076

AN - SCOPUS:30144436966

SN - 1523-7060

VL - 7

SP - 5825

EP - 5828

JO - Organic Letters

JF - Organic Letters

IS - 26

ER -

Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

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