Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

Shun Ying Liu; Lei Fang; Yong Bing He; Wing Hong Chan; Kai Tai Yeung; Yuen Kit Cheng; Rong Hua Yang

doi:10.1021/ol052341t

Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

Shun Ying Liu
, Lei Fang
, Yong Bing He
, Wing Hong Chan^*
, Kai Tai Yeung
, Yuen Kit Cheng
, Rong Hua Yang

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

132 Scopus citations

Abstract

(Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH₃OH/H₂O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 ⁶.

Original language	English
Pages (from-to)	5825-5828
Number of pages	4
Journal	Organic Letters
Volume	7
Issue number	26
DOIs	https://doi.org/10.1021/ol052341t
State	Published - 22 Dec 2005
Externally published	Yes

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title = "Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions",

abstract = "(Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 6.",

author = "Liu, \{Shun Ying\} and Lei Fang and He, \{Yong Bing\} and Chan, \{Wing Hong\} and Yeung, \{Kai Tai\} and Cheng, \{Yuen Kit\} and Yang, \{Rong Hua\}",

year = "2005",

month = dec,

day = "22",

doi = "10.1021/ol052341t",

language = "英语",

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pages = "5825--5828",

journal = "Organic Letters",

issn = "1523-7060",

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TY - JOUR

T1 - Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

AU - Liu, Shun Ying

AU - Fang, Lei

AU - He, Yong Bing

AU - Chan, Wing Hong

AU - Yeung, Kai Tai

AU - Cheng, Yuen Kit

AU - Yang, Rong Hua

PY - 2005/12/22

Y1 - 2005/12/22

N2 - (Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 6.

AB - (Figure Presented) The binding affinities of a cholic-acid-based fluorescent neutral receptor toward dicarboxylate anions and amino acids have been investigated in a CH3OH/H2O system (1:1, 0.01 M HEPES buffer, pH = 7.4) by fluorescence titration experiments. The synthetic host bearing four convergent functionalities strongly binds glutamate via multiple hydrogen bonds with a binding constant of (5.57 ± 0.88) × 10 6.

UR - https://www.scopus.com/pages/publications/30144436966

U2 - 10.1021/ol052341t

DO - 10.1021/ol052341t

M3 - 文章

C2 - 16354076

AN - SCOPUS:30144436966

SN - 1523-7060

VL - 7

SP - 5825

EP - 5828

JO - Organic Letters

JF - Organic Letters

IS - 26

ER -

Cholic-acid-based fluorescent sensor for dicarboxylates and acidic amino acids in aqueous solutions

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