Chiral tris(oxazoline)/Cu(ii) catalyzed coupling of terminal alkynes and nitrones

  • Meng Chun Ye
  • , Jian Zhou
  • , Zheng Zheng Huang
  • , Yong Tang*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

97 Scopus citations

Abstract

Novel chiral iPr-tris(oxazoline)/Cu(ClO4)2·6H2O catalyzed coupling of terminal acetylenes and nitrones to afford cis-disubstituted β-lactams is described; the choice of base proves essential to both the diastereoselectivity and the enantioselectivity.

Original languageEnglish
Pages (from-to)2554-2555
Number of pages2
JournalChemical Communications
Volume3
Issue number20
DOIs
StatePublished - 2003
Externally publishedYes

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