CdSe/ZnS quantum dot-Cytochrome c bioconjugates for selective intracellular O2- sensing

Da Wei Li; Li Xia Qin; Yang Li; Raheleh Partovi Nia; Yi Tao Long; Hong Yuan Chen

doi:10.1039/c1cc13160e

CdSe/ZnS quantum dot-Cytochrome c bioconjugates for selective intracellular O₂^- sensing

Da Wei Li
, Li Xia Qin
, Yang Li
, Raheleh Partovi Nia
, Yi Tao Long^*
, Hong Yuan Chen

^*Corresponding author for this work

East China University of Science and Technology
Western University
Nanjing University

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O₂^-) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.

Original language	English
Pages (from-to)	8539-8541
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	30
DOIs	https://doi.org/10.1039/c1cc13160e
State	Published - 14 Aug 2011
Externally published	Yes

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title = "CdSe/ZnS quantum dot-Cytochrome c bioconjugates for selective intracellular O2- sensing",

abstract = "We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O2-) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.",

author = "Li, \{Da Wei\} and Qin, \{Li Xia\} and Yang Li and Nia, \{Raheleh Partovi\} and Long, \{Yi Tao\} and Chen, \{Hong Yuan\}",

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doi = "10.1039/c1cc13160e",

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T1 - CdSe/ZnS quantum dot-Cytochrome c bioconjugates for selective intracellular O2- sensing

AU - Li, Da Wei

AU - Qin, Li Xia

AU - Li, Yang

AU - Nia, Raheleh Partovi

AU - Long, Yi Tao

AU - Chen, Hong Yuan

PY - 2011/8/14

Y1 - 2011/8/14

N2 - We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O2-) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.

AB - We demonstrate that the coupling system of negatively capped CdSe/ZnS QDs with an oxidized Cytochrome c (Cyt c) is capable of the fluorescent imaging of a superoxide radical (O2-) with high sensitivity and specificity in living cells, without interference from other Reactive Oxygen Species (ROS) or relevant intracellular components.

UR - https://www.scopus.com/pages/publications/79960488088

U2 - 10.1039/c1cc13160e

DO - 10.1039/c1cc13160e

M3 - 文章

C2 - 21709927

AN - SCOPUS:79960488088

SN - 1359-7345

VL - 47

SP - 8539

EP - 8541

JO - Chemical Communications

JF - Chemical Communications

IS - 30

ER -

CdSe/ZnS quantum dot-Cytochrome c bioconjugates for selective intracellular O₂^- sensing

Abstract

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