Catalytic gold nanoparticles for nanoplasmonic detection of DNA hybridization

  • Xiaoxue Zheng
  • , Qing Liu
  • , Chao Jing
  • , Yang Li
  • , Di Li*
  • , Weijie Luo
  • , Yanqin Wen
  • , Yao He
  • , Qing Huang
  • , Yi Tao Long
  • , Chunhai Fan
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

343 Scopus citations

Abstract

DNA hybridization can finely regulate the intrinsic glucose oxidase like catalytic activity of AuNPs owing to the marked difference in adsorption of single- and double-stranded DNA on its surface. A sensing strategy for DNA and microRNA is presented; in a different approach, this DNA-regulated AuNP catalysis was coupled with AuNP-mediated seed growth, which was monitored in real time and at a single-nanoparticle level.

Original languageEnglish
Pages (from-to)11994-11998
Number of pages5
JournalAngewandte Chemie - International Edition
Volume50
Issue number50
DOIs
StatePublished - 9 Dec 2011
Externally publishedYes

Keywords

  • DNA
  • catalysis
  • gold nanoparticles
  • microscopy
  • nanoplasmonics

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