Catalytic enantioselective synthesis of α-chiral azides

Pei Gang Ding; Xiao Si Hu; Feng Zhou; Jian Zhou

doi:10.1039/c8qo00138c

Catalytic enantioselective synthesis of α-chiral azides

Pei Gang Ding
, Xiao Si Hu
, Feng Zhou^*
, Jian Zhou

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

East China Normal University
CAS - Shanghai Institute of Organic Chemistry

Research output: Contribution to journal › Review article › peer-review

61 Scopus citations

Abstract

α-Chiral azides represent a special subclass of chiral amines, which not only widely exist in bioactive compounds but also play a significant role as a building block in a variety of value-added chiral products. The catalytic asymmetric synthesis of α-chiral azides is of current interest and three synthetic strategies have been developed. This review summarizes the recent progress in this research area, discusses the advantages and limitations of each strategy, and outlines synthetic opportunities for future research.

Original language	English
Pages (from-to)	1542-1559
Number of pages	18
Journal	Organic Chemistry Frontiers
Volume	5
Issue number	9
DOIs	https://doi.org/10.1039/c8qo00138c
State	Published - 2018

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title = "Catalytic enantioselective synthesis of α-chiral azides",

abstract = "α-Chiral azides represent a special subclass of chiral amines, which not only widely exist in bioactive compounds but also play a significant role as a building block in a variety of value-added chiral products. The catalytic asymmetric synthesis of α-chiral azides is of current interest and three synthetic strategies have been developed. This review summarizes the recent progress in this research area, discusses the advantages and limitations of each strategy, and outlines synthetic opportunities for future research.",

author = "Ding, \{Pei Gang\} and Hu, \{Xiao Si\} and Feng Zhou and Jian Zhou",

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AU - Ding, Pei Gang

AU - Hu, Xiao Si

AU - Zhou, Feng

AU - Zhou, Jian

PY - 2018

Y1 - 2018

N2 - α-Chiral azides represent a special subclass of chiral amines, which not only widely exist in bioactive compounds but also play a significant role as a building block in a variety of value-added chiral products. The catalytic asymmetric synthesis of α-chiral azides is of current interest and three synthetic strategies have been developed. This review summarizes the recent progress in this research area, discusses the advantages and limitations of each strategy, and outlines synthetic opportunities for future research.

AB - α-Chiral azides represent a special subclass of chiral amines, which not only widely exist in bioactive compounds but also play a significant role as a building block in a variety of value-added chiral products. The catalytic asymmetric synthesis of α-chiral azides is of current interest and three synthetic strategies have been developed. This review summarizes the recent progress in this research area, discusses the advantages and limitations of each strategy, and outlines synthetic opportunities for future research.

UR - https://www.scopus.com/pages/publications/85046259360

U2 - 10.1039/c8qo00138c

DO - 10.1039/c8qo00138c

M3 - 文献综述

AN - SCOPUS:85046259360

SN - 2052-4110

VL - 5

SP - 1542

EP - 1559

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

IS - 9

ER -

Catalytic enantioselective synthesis of α-chiral azides

Abstract

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