Catalytic cyanosilylation of ketones using organic catalyst 1,1,3,3-tetramethylguanidine

Lijia Wang; Xiao Huang; Jun Jiang; Xiaohua Liu; Xiaoming Feng

doi:10.1016/j.tetlet.2005.12.135

Catalytic cyanosilylation of ketones using organic catalyst 1,1,3,3-tetramethylguanidine

Lijia Wang
, Xiao Huang
, Jun Jiang
, Xiaohua Liu
, Xiaoming Feng^*

^*Corresponding author for this work

Sichuan University

Research output: Contribution to journal › Article › peer-review

63 Scopus citations

Abstract

1,1,3,3-Tetramethylguanidine acts as a highly effective catalyst for cyanosilylation of various ketones and aldehydes to the corresponding cyanohydrin trimethylsilyl ethers in up to 99% yield. The reaction proceeds smoothly with 0.1 mol % catalyst loading at 25°C under solvent-free conditions.

Original language	English
Pages (from-to)	1581-1584
Number of pages	4
Journal	Tetrahedron Letters
Volume	47
Issue number	10
DOIs	https://doi.org/10.1016/j.tetlet.2005.12.135
State	Published - 6 Mar 2006
Externally published	Yes

Access to Document

10.1016/j.tetlet.2005.12.135

Cite this

@article{ddea723a87204f098f06857a69e9ec2c,

title = "Catalytic cyanosilylation of ketones using organic catalyst 1,1,3,3-tetramethylguanidine",

abstract = "1,1,3,3-Tetramethylguanidine acts as a highly effective catalyst for cyanosilylation of various ketones and aldehydes to the corresponding cyanohydrin trimethylsilyl ethers in up to 99\% yield. The reaction proceeds smoothly with 0.1 mol \% catalyst loading at 25°C under solvent-free conditions.",

author = "Lijia Wang and Xiao Huang and Jun Jiang and Xiaohua Liu and Xiaoming Feng",

year = "2006",

month = mar,

day = "6",

doi = "10.1016/j.tetlet.2005.12.135",

language = "英语",

volume = "47",

pages = "1581--1584",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "10",

}

TY - JOUR

T1 - Catalytic cyanosilylation of ketones using organic catalyst 1,1,3,3-tetramethylguanidine

AU - Wang, Lijia

AU - Huang, Xiao

AU - Jiang, Jun

AU - Liu, Xiaohua

AU - Feng, Xiaoming

PY - 2006/3/6

Y1 - 2006/3/6

N2 - 1,1,3,3-Tetramethylguanidine acts as a highly effective catalyst for cyanosilylation of various ketones and aldehydes to the corresponding cyanohydrin trimethylsilyl ethers in up to 99% yield. The reaction proceeds smoothly with 0.1 mol % catalyst loading at 25°C under solvent-free conditions.

AB - 1,1,3,3-Tetramethylguanidine acts as a highly effective catalyst for cyanosilylation of various ketones and aldehydes to the corresponding cyanohydrin trimethylsilyl ethers in up to 99% yield. The reaction proceeds smoothly with 0.1 mol % catalyst loading at 25°C under solvent-free conditions.

UR - https://www.scopus.com/pages/publications/31944432616

U2 - 10.1016/j.tetlet.2005.12.135

DO - 10.1016/j.tetlet.2005.12.135

M3 - 文章

AN - SCOPUS:31944432616

SN - 0040-4039

VL - 47

SP - 1581

EP - 1584

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

Catalytic cyanosilylation of ketones using organic catalyst 1,1,3,3-tetramethylguanidine

Abstract

Access to Document

Other files and links

Fingerprint

Cite this