Catalytic asymmetric reductive animation of α-branched ketones

Vijay N. Wakchaure; Jian Zhou; Sebastian Hoffmann; Benjamin List

doi:10.1002/anie.201001715

Catalytic asymmetric reductive animation of α-branched ketones

Vijay N. Wakchaure
, Jian Zhou
, Sebastian Hoffmann
, Benjamin List

Max Planck Institute for Coal Research

Research output: Contribution to journal › Article › peer-review

133 Scopus citations

Abstract

Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.

Original language	English
Pages (from-to)	4612-4614
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	27
DOIs	https://doi.org/10.1002/anie.201001715
State	Published - 21 Jun 2010
Externally published	Yes

Keywords

Asymmetric catalysis
Chiral amines
Ketones
Organocatalysis
Reductive amination

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10.1002/anie.201001715

Cite this

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title = "Catalytic asymmetric reductive animation of α-branched ketones",

abstract = "Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.",

keywords = "Asymmetric catalysis, Chiral amines, Ketones, Organocatalysis, Reductive amination",

author = "Wakchaure, \{Vijay N.\} and Jian Zhou and Sebastian Hoffmann and Benjamin List",

year = "2010",

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T1 - Catalytic asymmetric reductive animation of α-branched ketones

AU - Wakchaure, Vijay N.

AU - Zhou, Jian

AU - Hoffmann, Sebastian

AU - List, Benjamin

PY - 2010/6/21

Y1 - 2010/6/21

N2 - Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.

AB - Chemical equcation Presented Branching out: An organocatalytic reductive amination of -αbranched ketones using dynamic kinetic resolution is reported. The e/s-2-substituted cyclohexyl amines were obtained in high diastereoselectivity and enantioselectivity from the corresponding ketones.

KW - Asymmetric catalysis

KW - Chiral amines

KW - Ketones

KW - Organocatalysis

KW - Reductive amination

UR - https://www.scopus.com/pages/publications/77953948379

U2 - 10.1002/anie.201001715

DO - 10.1002/anie.201001715

M3 - 文章

AN - SCOPUS:77953948379

SN - 1433-7851

VL - 49

SP - 4612

EP - 4614

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 27

ER -

Catalytic asymmetric reductive animation of α-branched ketones

Abstract

Keywords

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