Catalytic and enantioselective α-functionalization of oxindoles through oxidative reactions with naphthoquinones

Woon Yew Siau; Wenjun Li; Fei Xue; Qiao Ren; Minghu Wu; Shaofa Sun; Haibing Guo; Xuefeng Jiang; Jian Wang

doi:10.1002/chem.201200206

Catalytic and enantioselective α-functionalization of oxindoles through oxidative reactions with naphthoquinones

Woon Yew Siau
, Wenjun Li
, Fei Xue
, Qiao Ren
, Minghu Wu
, Shaofa Sun
, Haibing Guo^*
, Xuefeng Jiang
, Jian Wang

^*Corresponding author for this work

School of Chemistry and Molecular Engineering

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

Strong as an oxindole: The enantioselective assembly of 3,3-disubstituted oxindoles is an attractive and valuable target because of the unique properties of the oxindole core. A new organocatalyzed and enantioselective aerobic oxidative strategy for the assembly of this core structure from oxindoles and simple naphthoquinones is reported (see scheme).

Original language	English
Pages (from-to)	9491-9495
Number of pages	5
Journal	Chemistry - A European Journal
Volume	18
Issue number	31
DOIs	https://doi.org/10.1002/chem.201200206
State	Published - 27 Jul 2012

Keywords

asymmetric catalysis
indane
organocatalysis
oxindole
thiourea

Access to Document

10.1002/chem.201200206

Cite this

@article{6943bcbf54414fe5b51412929f4e7a05,

title = "Catalytic and enantioselective α-functionalization of oxindoles through oxidative reactions with naphthoquinones",

abstract = "Strong as an oxindole: The enantioselective assembly of 3,3-disubstituted oxindoles is an attractive and valuable target because of the unique properties of the oxindole core. A new organocatalyzed and enantioselective aerobic oxidative strategy for the assembly of this core structure from oxindoles and simple naphthoquinones is reported (see scheme).",

keywords = "asymmetric catalysis, indane, organocatalysis, oxindole, thiourea",

author = "Siau, \{Woon Yew\} and Wenjun Li and Fei Xue and Qiao Ren and Minghu Wu and Shaofa Sun and Haibing Guo and Xuefeng Jiang and Jian Wang",

year = "2012",

month = jul,

day = "27",

doi = "10.1002/chem.201200206",

language = "英语",

volume = "18",

pages = "9491--9495",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "John Wiley and Sons Inc",

number = "31",

}

TY - JOUR

T1 - Catalytic and enantioselective α-functionalization of oxindoles through oxidative reactions with naphthoquinones

AU - Siau, Woon Yew

AU - Li, Wenjun

AU - Xue, Fei

AU - Ren, Qiao

AU - Wu, Minghu

AU - Sun, Shaofa

AU - Guo, Haibing

AU - Jiang, Xuefeng

AU - Wang, Jian

PY - 2012/7/27

Y1 - 2012/7/27

N2 - Strong as an oxindole: The enantioselective assembly of 3,3-disubstituted oxindoles is an attractive and valuable target because of the unique properties of the oxindole core. A new organocatalyzed and enantioselective aerobic oxidative strategy for the assembly of this core structure from oxindoles and simple naphthoquinones is reported (see scheme).

AB - Strong as an oxindole: The enantioselective assembly of 3,3-disubstituted oxindoles is an attractive and valuable target because of the unique properties of the oxindole core. A new organocatalyzed and enantioselective aerobic oxidative strategy for the assembly of this core structure from oxindoles and simple naphthoquinones is reported (see scheme).

KW - asymmetric catalysis

KW - indane

KW - organocatalysis

KW - oxindole

KW - thiourea

UR - https://www.scopus.com/pages/publications/84864151866

U2 - 10.1002/chem.201200206

DO - 10.1002/chem.201200206

M3 - 文章

AN - SCOPUS:84864151866

SN - 0947-6539

VL - 18

SP - 9491

EP - 9495

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 31

ER -

Catalytic and enantioselective α-functionalization of oxindoles through oxidative reactions with naphthoquinones

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this