Catalytic acylcyanation of imines with acetylcyanide

Subhas Chandra Pan; Jian Zhou; Benjamin List

doi:10.1055/s-2006-951543

Catalytic acylcyanation of imines with acetylcyanide

Subhas Chandra Pan
, Jian Zhou
, Benjamin List^*

^*Corresponding author for this work

Max Planck Institute for Coal Research

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.

Original language	English
Pages (from-to)	3275-3276
Number of pages	2
Journal	Synlett
Issue number	19
DOIs	https://doi.org/10.1055/s-2006-951543
State	Published - 1 Dec 2006
Externally published	Yes

Keywords

Acetyl cyanide
Acylcyanation
Brønsted acid catalysis
Organocatalysis
α-amino nitrile

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10.1055/s-2006-951543

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@article{b6885c9598ab4d068cdca3d443146be9,

title = "Catalytic acylcyanation of imines with acetylcyanide",

abstract = "Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.",

keywords = "Acetyl cyanide, Acylcyanation, Br{\o}nsted acid catalysis, Organocatalysis, α-amino nitrile",

author = "Pan, \{Subhas Chandra\} and Jian Zhou and Benjamin List",

year = "2006",

month = dec,

day = "1",

doi = "10.1055/s-2006-951543",

language = "英语",

pages = "3275--3276",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "19",

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TY - JOUR

T1 - Catalytic acylcyanation of imines with acetylcyanide

AU - Pan, Subhas Chandra

AU - Zhou, Jian

AU - List, Benjamin

PY - 2006/12/1

Y1 - 2006/12/1

N2 - Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.

AB - Aldimines react with acetyl cyanide in the presence of a catalytic amount of a thiourea catalyst to give the corresponding N-acetylated amino nitriles in high yields. The scope of the reaction is broad and both aromatic as well as aliphatic aldimines can readily be used.

KW - Acetyl cyanide

KW - Acylcyanation

KW - Brønsted acid catalysis

KW - Organocatalysis

KW - α-amino nitrile

UR - https://www.scopus.com/pages/publications/33845634715

U2 - 10.1055/s-2006-951543

DO - 10.1055/s-2006-951543

M3 - 文章

AN - SCOPUS:33845634715

SN - 0936-5214

SP - 3275

EP - 3276

JO - Synlett

JF - Synlett

IS - 19

ER -

Catalytic acylcyanation of imines with acetylcyanide

Abstract

Keywords

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