Carbon dot-based inorganic-organic nanosystem for two-photon imaging and biosensing of pH variation in living cells and tissues

Biao Kong; Anwei Zhu; Changqin Ding; Xiaoming Zhao; Bo Li; Yang Tian

doi:10.1002/adma.201202599

Carbon dot-based inorganic-organic nanosystem for two-photon imaging and biosensing of pH variation in living cells and tissues

Biao Kong
, Anwei Zhu
, Changqin Ding
, Xiaoming Zhao
, Bo Li
, Yang Tian^*

^*Corresponding author for this work

School of Physics and Electronic Science

Tongji University

Research output: Contribution to journal › Article › peer-review

547 Scopus citations

Abstract

A carbon dot (C-Dot)-based two-photon fluorescent probe has been developed for the monitoring of pH changes across a broad range with high sensitivity and selectivity. The inorganic-organic probe also shows good biocompatibility and cell permeability, and thus can be successfully applied in bioimaging and biosensing of physiological pH in living cells, as well as living tissues at a depth of 65-185 μm.

Original language	English
Pages (from-to)	5844-5848
Number of pages	5
Journal	Advanced Materials
Volume	24
Issue number	43
DOIs	https://doi.org/10.1002/adma.201202599
State	Published - 14 Nov 2012

Keywords

biosensors
carbon dots
cells
tissues
two-photon spectroscopy

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10.1002/adma.201202599

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T1 - Carbon dot-based inorganic-organic nanosystem for two-photon imaging and biosensing of pH variation in living cells and tissues

AU - Kong, Biao

AU - Zhu, Anwei

AU - Ding, Changqin

AU - Zhao, Xiaoming

AU - Li, Bo

AU - Tian, Yang

PY - 2012/11/14

Y1 - 2012/11/14

N2 - A carbon dot (C-Dot)-based two-photon fluorescent probe has been developed for the monitoring of pH changes across a broad range with high sensitivity and selectivity. The inorganic-organic probe also shows good biocompatibility and cell permeability, and thus can be successfully applied in bioimaging and biosensing of physiological pH in living cells, as well as living tissues at a depth of 65-185 μm.

AB - A carbon dot (C-Dot)-based two-photon fluorescent probe has been developed for the monitoring of pH changes across a broad range with high sensitivity and selectivity. The inorganic-organic probe also shows good biocompatibility and cell permeability, and thus can be successfully applied in bioimaging and biosensing of physiological pH in living cells, as well as living tissues at a depth of 65-185 μm.

KW - biosensors

KW - carbon dots

KW - cells

KW - tissues

KW - two-photon spectroscopy

UR - https://www.scopus.com/pages/publications/84868686521

U2 - 10.1002/adma.201202599

DO - 10.1002/adma.201202599

M3 - 文章

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AN - SCOPUS:84868686521

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JO - Advanced Materials

JF - Advanced Materials

IS - 43

ER -

Carbon dot-based inorganic-organic nanosystem for two-photon imaging and biosensing of pH variation in living cells and tissues

Abstract

Keywords

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