Capture of circulating tumor cells with superhydrophilic silicon dioxide nano pillar structure without capture antibodies

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Abstract

This paper reports a simple, yet effective method for capturing circulating tumor cells (CTCs) without using any capture antibodies. A simple way to fabricate silicon dioxide nano pillar structure with superhydrophilic properties has been developed. We demonstrate that our fabricated structure could efficiently capture cancer cells (A549 and H1975) without using any capture antibodies. Our results show that the silicon dioxide nano pillar structure enhances CTCs capture yield up to 65% within 4h of cell incubation.

Original languageEnglish
Title of host publicationIEEE-NANO 2015 - 15th International Conference on Nanotechnology
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages854-857
Number of pages4
ISBN (Electronic)9781467381550
DOIs
StatePublished - 2015
Externally publishedYes
Event15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015 - Rome, Italy
Duration: 27 Jul 201530 Jul 2015

Publication series

NameIEEE-NANO 2015 - 15th International Conference on Nanotechnology

Conference

Conference15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015
Country/TerritoryItaly
CityRome
Period27/07/1530/07/15

Keywords

  • cell capture
  • circulating tumor cells
  • nano pillar

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