Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

Jinlou Gu; Meng Huang; Jiapeng Liu; Yongsheng Li; Wenru Zhao; Jianlin Shi

doi:10.1039/c2nj40482f

Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

Jinlou Gu^*
, Meng Huang
, Jiapeng Liu
, Yongsheng Li
, Wenru Zhao
, Jianlin Shi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.

Original language	English
Pages (from-to)	1717-1720
Number of pages	4
Journal	New Journal of Chemistry
Volume	36
Issue number	9
DOIs	https://doi.org/10.1039/c2nj40482f
State	Published - Sep 2012
Externally published	Yes

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10.1039/c2nj40482f

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@article{19785c820b27460e9fcf1fc2cd874c1f,

title = "Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles",

abstract = "Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.",

author = "Jinlou Gu and Meng Huang and Jiapeng Liu and Yongsheng Li and Wenru Zhao and Jianlin Shi",

year = "2012",

month = sep,

doi = "10.1039/c2nj40482f",

language = "英语",

volume = "36",

pages = "1717--1720",

journal = "New Journal of Chemistry",

issn = "1144-0546",

publisher = "Royal Society of Chemistry",

number = "9",

}

TY - JOUR

T1 - Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

AU - Gu, Jinlou

AU - Huang, Meng

AU - Liu, Jiapeng

AU - Li, Yongsheng

AU - Zhao, Wenru

AU - Shi, Jianlin

PY - 2012/9

Y1 - 2012/9

N2 - Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.

AB - Calcium doped mesoporous silica nanoparticles were successfully prepared and employed as efficient drug carriers for alendronate delivery. The incorporation of calcium ions dramatically enhanced the drug loading capacity and sustained release rate. The loaded alendronate more efficiently inhibited the growth of HeLa cancer cells than free drug.

UR - https://www.scopus.com/pages/publications/84865116926

U2 - 10.1039/c2nj40482f

DO - 10.1039/c2nj40482f

M3 - 文章

AN - SCOPUS:84865116926

SN - 1144-0546

VL - 36

SP - 1717

EP - 1720

JO - New Journal of Chemistry

JF - New Journal of Chemistry

IS - 9

ER -

Calcium doped mesoporous silica nanoparticles as efficient alendronate delivery vehicles

Abstract

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