Broad-band excitation in indirectly detected 14N overtone spectroscopy with composite pulses

Ming Shen; Qun Chen; Jean Paul Amoureux; Bingwen Hu

doi:10.1016/j.ssnmr.2016.05.001

Broad-band excitation in indirectly detected ¹⁴N overtone spectroscopy with composite pulses

Ming Shen
, Qun Chen
, Jean Paul Amoureux
, Bingwen Hu^*

^*Corresponding author for this work

School of Physics and Electronic Science

East China Normal University

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

We show here that composite pulses allow broad-band excitation of nitrogen-14 overtone frequencies in proton detected D-HMQC experiments (referred to ¹H-{¹⁴N_OT^DQ} D-HMQC). Experimental verifications have been performed on glycine, L-histidine and N-acetyl-valine (NAV) samples. Composite pulses enable symmetric excitations of ¹⁴N sites with large shift differences. Therefore, this approach is promising for recording high resolution ¹H-{¹⁴N_OT^DQ} D-HMQC spectra of most amino-acids, pharmaceutical samples and peptides.

Original language	English
Pages (from-to)	5-8
Number of pages	4
Journal	Solid State Nuclear Magnetic Resonance
Volume	78
DOIs	https://doi.org/10.1016/j.ssnmr.2016.05.001
State	Published - 1 Sep 2016

Keywords

N overtone spectroscopy
Proton-detected D-HMQC
Solid-state NMR

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10.1016/j.ssnmr.2016.05.001

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@article{779439ccc7ea470d94b90bf9f90fe80e,

title = "Broad-band excitation in indirectly detected 14N overtone spectroscopy with composite pulses",

abstract = "We show here that composite pulses allow broad-band excitation of nitrogen-14 overtone frequencies in proton detected D-HMQC experiments (referred to 1H-\{14NOTDQ\} D-HMQC). Experimental verifications have been performed on glycine, L-histidine and N-acetyl-valine (NAV) samples. Composite pulses enable symmetric excitations of 14N sites with large shift differences. Therefore, this approach is promising for recording high resolution 1H-\{14NOTDQ\} D-HMQC spectra of most amino-acids, pharmaceutical samples and peptides.",

keywords = "N overtone spectroscopy, Proton-detected D-HMQC, Solid-state NMR",

author = "Ming Shen and Qun Chen and Amoureux, \{Jean Paul\} and Bingwen Hu",

year = "2016",

month = sep,

day = "1",

doi = "10.1016/j.ssnmr.2016.05.001",

language = "英语",

volume = "78",

pages = "5--8",

journal = "Solid State Nuclear Magnetic Resonance",

issn = "0926-2040",

publisher = "Elsevier B.V.",

}

TY - JOUR

T1 - Broad-band excitation in indirectly detected 14N overtone spectroscopy with composite pulses

AU - Shen, Ming

AU - Chen, Qun

AU - Amoureux, Jean Paul

AU - Hu, Bingwen

PY - 2016/9/1

Y1 - 2016/9/1

N2 - We show here that composite pulses allow broad-band excitation of nitrogen-14 overtone frequencies in proton detected D-HMQC experiments (referred to 1H-{14NOTDQ} D-HMQC). Experimental verifications have been performed on glycine, L-histidine and N-acetyl-valine (NAV) samples. Composite pulses enable symmetric excitations of 14N sites with large shift differences. Therefore, this approach is promising for recording high resolution 1H-{14NOTDQ} D-HMQC spectra of most amino-acids, pharmaceutical samples and peptides.

AB - We show here that composite pulses allow broad-band excitation of nitrogen-14 overtone frequencies in proton detected D-HMQC experiments (referred to 1H-{14NOTDQ} D-HMQC). Experimental verifications have been performed on glycine, L-histidine and N-acetyl-valine (NAV) samples. Composite pulses enable symmetric excitations of 14N sites with large shift differences. Therefore, this approach is promising for recording high resolution 1H-{14NOTDQ} D-HMQC spectra of most amino-acids, pharmaceutical samples and peptides.

KW - N overtone spectroscopy

KW - Proton-detected D-HMQC

KW - Solid-state NMR

UR - https://www.scopus.com/pages/publications/84975251691

U2 - 10.1016/j.ssnmr.2016.05.001

DO - 10.1016/j.ssnmr.2016.05.001

M3 - 文章

C2 - 27322031

AN - SCOPUS:84975251691

SN - 0926-2040

VL - 78

SP - 5

EP - 8

JO - Solid State Nuclear Magnetic Resonance

JF - Solid State Nuclear Magnetic Resonance

ER -

Broad-band excitation in indirectly detected ¹⁴N overtone spectroscopy with composite pulses

Abstract

Keywords

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