Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery

Yannan Yang; Yuting Niu; Jun Zhang; Anand Kumar Meka; Hongwei Zhang; Chun Xu; Chun Xiang Cynthia Lin; Meihua Yu; Chengzhong Yu

doi:10.1002/smll.201402779

Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery

Yannan Yang
, Yuting Niu
, Jun Zhang
, Anand Kumar Meka
, Hongwei Zhang
, Chun Xu
, Chun Xiang Cynthia Lin
, Meihua Yu
, Chengzhong Yu^*

^*Corresponding author for this work

University of Queensland

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

Large pore (4.6-7.6 nm) and well-dispersed benzene bridged mesoporous organosilica nanoparticles with uniform particle size of ≈50 nm are prepared via a biphasic approach. They can be directly used as nanocarriers without surface modification for the intracellular delivery of therapeutic proteins.

Original language	English
Pages (from-to)	2743-2749
Number of pages	7
Journal	Small
Volume	11
Issue number	23
DOIs	https://doi.org/10.1002/smll.201402779
State	Published - 1 Jun 2015
Externally published	Yes

Keywords

biphasic synthesis
large pores
mesoporous organosilica nanoparticles
protein delivery

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10.1002/smll.201402779

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title = "Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery",

abstract = "Large pore (4.6-7.6 nm) and well-dispersed benzene bridged mesoporous organosilica nanoparticles with uniform particle size of ≈50 nm are prepared via a biphasic approach. They can be directly used as nanocarriers without surface modification for the intracellular delivery of therapeutic proteins.",

keywords = "biphasic synthesis, large pores, mesoporous organosilica nanoparticles, protein delivery",

author = "Yannan Yang and Yuting Niu and Jun Zhang and Meka, \{Anand Kumar\} and Hongwei Zhang and Chun Xu and Lin, \{Chun Xiang Cynthia\} and Meihua Yu and Chengzhong Yu",

note = "Publisher Copyright: {\textcopyright} 2015 WILEY-VCH Verlag GmbH \& Co. KGaA, Weinheim.",

year = "2015",

month = jun,

day = "1",

doi = "10.1002/smll.201402779",

language = "英语",

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journal = "Small",

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publisher = "Wiley-VCH Verlag",

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TY - JOUR

T1 - Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery

AU - Yang, Yannan

AU - Niu, Yuting

AU - Zhang, Jun

AU - Meka, Anand Kumar

AU - Zhang, Hongwei

AU - Xu, Chun

AU - Lin, Chun Xiang Cynthia

AU - Yu, Meihua

AU - Yu, Chengzhong

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Large pore (4.6-7.6 nm) and well-dispersed benzene bridged mesoporous organosilica nanoparticles with uniform particle size of ≈50 nm are prepared via a biphasic approach. They can be directly used as nanocarriers without surface modification for the intracellular delivery of therapeutic proteins.

AB - Large pore (4.6-7.6 nm) and well-dispersed benzene bridged mesoporous organosilica nanoparticles with uniform particle size of ≈50 nm are prepared via a biphasic approach. They can be directly used as nanocarriers without surface modification for the intracellular delivery of therapeutic proteins.

KW - biphasic synthesis

KW - large pores

KW - mesoporous organosilica nanoparticles

KW - protein delivery

UR - https://www.scopus.com/pages/publications/84934978441

U2 - 10.1002/smll.201402779

DO - 10.1002/smll.201402779

M3 - 文章

C2 - 25652950

AN - SCOPUS:84934978441

SN - 1613-6810

VL - 11

SP - 2743

EP - 2749

JO - Small

JF - Small

IS - 23

ER -

Biphasic Synthesis of Large-Pore and Well-Dispersed Benzene Bridged Mesoporous Organosilica Nanoparticles for Intracellular Protein Delivery

Abstract

Keywords

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